RET

ENSG00000165731 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0004872 receptor activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0005178 integrin binding

Drugs

Drug name Description
CABOZANTINIB
LENVATINIB
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor
SUNITINIB Macrophage colony stimulating factor receptor inhibitor
VANDETANIB Epidermal growth factor receptor inhibitor

Diseases

Disease Name
medullary thyroid
papillary thyroid
pheochromocytoma
NSCLC
Spitzoid tumour

Orthologs

No orthologs in record

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000061273 HDAC7 ENSG00000165731 RET H. sapiens SSL Slorth 0.965946 View
ENSG00000082898 XPO1 ENSG00000165731 RET H. sapiens SSL Slorth 0.96565 View
ENSG00000139687 RB1 ENSG00000165731 RET H. sapiens SDL Slorth 0.965593 View
ENSG00000165731 RET ENSG00000184937 WT1 H. sapiens SDL Slorth 0.965421 View
ENSG00000165731 RET ENSG00000184012 TMPRSS2 H. sapiens SDL Slorth 0.96525 View
ENSG00000100644 HIF1A ENSG00000165731 RET H. sapiens SDL Slorth 0.965193 View
ENSG00000097046 CDC7 ENSG00000165731 RET H. sapiens SSL Slorth 0.965028 View
ENSG00000165731 RET ENSG00000206181 TCEB3B H. sapiens SDL Slorth 0.964807 View
ENSG00000121879 PIK3CA ENSG00000165731 RET H. sapiens SSL Slorth 0.964719 View
ENSG00000004700 RECQL ENSG00000165731 RET H. sapiens SSL Slorth 0.96471 View
ENSG00000162385 MAGOH ENSG00000165731 RET H. sapiens SDL Slorth 0.964595 View
ENSG00000165731 RET ENSG00000168036 CTNNB1 H. sapiens SDL Slorth 0.964451 View
ENSG00000132155 RAF1 ENSG00000165731 RET H. sapiens SSL Slorth 0.964349 View
ENSG00000148400 NOTCH1 ENSG00000165731 RET H. sapiens SSL Slorth 0.964219 View
ENSG00000165731 RET ENSG00000171150 SOCS5 H. sapiens SDL Slorth 0.964185 View
ENSG00000165731 RET ENSG00000256223 ZNF10 H. sapiens SDL Slorth 0.964007 View
ENSG00000165731 RET ENSG00000172367 PDZD3 H. sapiens SDL Slorth 0.963955 View
ENSG00000069869 NEDD4 ENSG00000165731 RET H. sapiens SSL Slorth 0.963951 View
ENSG00000010810 FYN ENSG00000165731 RET H. sapiens SSL Slorth 0.963711 View
ENSG00000157764 BRAF ENSG00000165731 RET H. sapiens SSL Slorth 0.9637 View
ENSG00000165731 RET ENSG00000166341 DCHS1 H. sapiens SDL Slorth 0.963633 View
ENSG00000165731 RET ENSG00000169926 KLF13 H. sapiens SDL Slorth 0.963345 View
ENSG00000165731 RET ENSG00000240771 ARHGEF25 H. sapiens SDL Slorth 0.963217 View
ENSG00000165731 RET ENSG00000205629 LCMT1 H. sapiens SDL Slorth 0.962788 View
ENSG00000165731 RET ENSG00000198353 HOXC4 H. sapiens SDL Slorth 0.962241 View
ENSG00000100030 MAPK1 ENSG00000165731 RET H. sapiens SSL Slorth 0.962124 View
ENSG00000165731 RET ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.961935 View
ENSG00000080815 PSEN1 ENSG00000165731 RET H. sapiens SSL Slorth 0.961681 View
ENSG00000150093 ITGB1 ENSG00000165731 RET H. sapiens SSL Slorth 0.961554 View
ENSG00000113721 PDGFRB ENSG00000165731 RET H. sapiens SSL Slorth 0.961504 View
ENSG00000110330 BIRC2 ENSG00000165731 RET H. sapiens SSL Slorth 0.961493 View
ENSG00000165731 RET ENSG00000173404 INSM1 H. sapiens SDL Slorth 0.961083 View
ENSG00000097007 ABL1 ENSG00000165731 RET H. sapiens SDL Slorth 0.960786 View
ENSG00000101868 POLA1 ENSG00000165731 RET H. sapiens SSL Slorth 0.960757 View
ENSG00000065559 MAP2K4 ENSG00000165731 RET H. sapiens SSL Slorth 0.960721 View
ENSG00000109906 ZBTB16 ENSG00000165731 RET H. sapiens SSL Slorth 0.960534 View
ENSG00000165731 RET ENSG00000184470 TXNRD2 H. sapiens SDL Slorth 0.960404 View
ENSG00000165025 SYK ENSG00000165731 RET H. sapiens SSL Slorth 0.960117 View
ENSG00000089159 PXN ENSG00000165731 RET H. sapiens SSL Slorth 0.959929 View
ENSG00000127022 CANX ENSG00000165731 RET H. sapiens SSL Slorth 0.959845 View