ERBB3

ENSG00000065361 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004888 transmembrane signaling receptor activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0019838 growth factor binding
GO:0030296 protein tyrosine kinase activator activity
GO:0038132 neuregulin binding
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity
GO:0046982 protein heterodimerization activity

Drugs

Drug name Description
VANDETANIB Epidermal growth factor receptor inhibitor

Diseases

Disease Name
colon
gastric
head and neck
bladder
skin

Orthologs

Gene Organism
let-23 C. elegans
Egfr D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000065361 ERBB3 ENSG00000186298 PPP1CC H. sapiens SSL BioGRID 1.0 View
ENSG00000065361 ERBB3 ENSG00000100033 PRODH H. sapiens SSL BioGRID 1.0 View
ENSG00000065361 ERBB3 ENSG00000052344 PRSS8 H. sapiens SSL BioGRID 1.0 View
ENSG00000012048 BRCA1 ENSG00000065361 ERBB3 H. sapiens SDL Slorth 0.985828 View
ENSG00000065361 ERBB3 ENSG00000142208 AKT1 H. sapiens SDL Slorth 0.980191 View
ENSG00000065361 ERBB3 ENSG00000169083 AR H. sapiens SDL Slorth 0.978567 View
ENSG00000005339 CREBBP ENSG00000065361 ERBB3 H. sapiens SDL Slorth 0.97732 View
ENSG00000065361 ERBB3 ENSG00000150991 UBC H. sapiens SDL Slorth 0.976778 View
ENSG00000065361 ERBB3 ENSG00000197122 SRC H. sapiens SDL Slorth 0.973798 View
ENSG00000065361 ERBB3 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.973526 View
ENSG00000065361 ERBB3 ENSG00000146648 EGFR H. sapiens SDL Slorth 0.973495 View
ENSG00000065361 ERBB3 ENSG00000168036 CTNNB1 H. sapiens SDL Slorth 0.972105 View
ENSG00000065361 ERBB3 ENSG00000080824 HSP90AA1 H. sapiens SDL Slorth 0.971288 View
ENSG00000065361 ERBB3 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.96949 View
ENSG00000065361 ERBB3 ENSG00000132646 PCNA H. sapiens SDL Slorth 0.968213 View
ENSG00000065361 ERBB3 ENSG00000139687 RB1 H. sapiens SDL Slorth 0.965819 View
ENSG00000065361 ERBB3 ENSG00000170315 UBB H. sapiens SDL Slorth 0.964498 View
ENSG00000065361 ERBB3 ENSG00000177885 GRB2 H. sapiens SDL Slorth 0.960757 View
ENSG00000012048 BRCA1 ENSG00000065361 ERBB3 H. sapiens SSL Slorth 0.960617 View
ENSG00000065361 ERBB3 ENSG00000100393 EP300 H. sapiens SDL Slorth 0.95919 View
ENSG00000065361 ERBB3 ENSG00000141510 TP53 H. sapiens SDL Slorth 0.958978 View
ENSG00000065361 ERBB3 ENSG00000136997 MYC H. sapiens SDL Slorth 0.957496 View
ENSG00000065361 ERBB3 ENSG00000110395 CBL H. sapiens SDL Slorth 0.953196 View
ENSG00000004700 RECQL ENSG00000065361 ERBB3 H. sapiens SSL Slorth 0.950917 View
ENSG00000065361 ERBB3 ENSG00000116478 HDAC1 H. sapiens SDL Slorth 0.950537 View
ENSG00000062822 POLD1 ENSG00000065361 ERBB3 H. sapiens SSL Slorth 0.946913 View
ENSG00000065361 ERBB3 ENSG00000101266 CSNK2A1 H. sapiens SDL Slorth 0.9411 View
ENSG00000001626 CFTR ENSG00000065361 ERBB3 H. sapiens SSL Slorth 0.93928 View
ENSG00000065361 ERBB3 ENSG00000177606 JUN H. sapiens SDL Slorth 0.934636 View
ENSG00000005339 CREBBP ENSG00000065361 ERBB3 H. sapiens SSL Slorth 0.933666 View
ENSG00000065361 ERBB3 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.932305 View
ENSG00000065361 ERBB3 ENSG00000168610 STAT3 H. sapiens SDL Slorth 0.931044 View
ENSG00000010810 FYN ENSG00000065361 ERBB3 H. sapiens SSL Slorth 0.927265 View
ENSG00000065361 ERBB3 ENSG00000162385 MAGOH H. sapiens SDL Slorth 0.923452 View
ENSG00000065361 ERBB3 ENSG00000100030 MAPK1 H. sapiens SDL Slorth 0.923294 View
ENSG00000065361 ERBB3 ENSG00000221983 UBA52 H. sapiens SDL Slorth 0.919011 View
ENSG00000065361 ERBB3 ENSG00000185591 SP1 H. sapiens SDL Slorth 0.914729 View
ENSG00000065361 ERBB3 ENSG00000109971 HSPA8 H. sapiens SDL Slorth 0.913488 View
ENSG00000065361 ERBB3 ENSG00000198400 NTRK1 H. sapiens SDL Slorth 0.913008 View
ENSG00000065361 ERBB3 ENSG00000196961 AP2A1 H. sapiens SDL Slorth 0.900097 View