CYP3A4

ENSG00000160868 - H. sapiens

Pathways

Go term Description
GO:0004497 monooxygenase activity
GO:0005496 steroid binding
GO:0005506 iron ion binding
GO:0008395 steroid hydroxylase activity
GO:0016491 oxidoreductase activity
GO:0019825 oxygen binding
GO:0019899 enzyme binding
GO:0020037 heme binding
GO:0030343 vitamin D3 25-hydroxylase activity
GO:0033780 taurochenodeoxycholate 6alpha-hydroxylase activity
GO:0034875 caffeine oxidase activity
GO:0047638 albendazole monooxygenase activity
GO:0050591 quinine 3-monooxygenase activity
GO:0050649 testosterone 6-beta-hydroxylase activity
GO:0070330 aromatase activity
GO:0070576 vitamin D 24-hydroxylase activity
GO:0101020 estrogen 16-alpha-hydroxylase activity
GO:0102320 1,8-cineole 2-exo-monooxygenase activity

Drugs

Drug name Description
COBICISTAT Cytochrome P450 3A inhibitor

Diseases

No diseases in record

Orthologs

Gene Organism
Cyp6a9 D. melanogaster
Cyp6a22 D. melanogaster
Cyp6a21 D. melanogaster
Cyp28d1 D. melanogaster
Cyp28d2 D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000142208 AKT1 ENSG00000160868 CYP3A4 H. sapiens SDL Slorth 0.98308 View
ENSG00000133703 KRAS ENSG00000160868 CYP3A4 H. sapiens SSL Slorth 0.979405 View
ENSG00000141510 TP53 ENSG00000160868 CYP3A4 H. sapiens SDL Slorth 0.979329 View
ENSG00000132646 PCNA ENSG00000160868 CYP3A4 H. sapiens SDL Slorth 0.979013 View
ENSG00000012048 BRCA1 ENSG00000160868 CYP3A4 H. sapiens SDL Slorth 0.978732 View
ENSG00000109670 FBXW7 ENSG00000160868 CYP3A4 H. sapiens SSL Slorth 0.977007 View
ENSG00000103275 UBE2I ENSG00000160868 CYP3A4 H. sapiens SDL Slorth 0.976936 View
ENSG00000146648 EGFR ENSG00000160868 CYP3A4 H. sapiens SDL Slorth 0.97677 View
ENSG00000116478 HDAC1 ENSG00000160868 CYP3A4 H. sapiens SDL Slorth 0.976682 View
ENSG00000160868 CYP3A4 ENSG00000168036 CTNNB1 H. sapiens SDL Slorth 0.976452 View
ENSG00000132155 RAF1 ENSG00000160868 CYP3A4 H. sapiens SDL Slorth 0.974777 View
ENSG00000091831 ESR1 ENSG00000160868 CYP3A4 H. sapiens SDL Slorth 0.974282 View
ENSG00000160868 CYP3A4 ENSG00000169083 AR H. sapiens SDL Slorth 0.971808 View
ENSG00000100030 MAPK1 ENSG00000160868 CYP3A4 H. sapiens SDL Slorth 0.968855 View
ENSG00000160868 CYP3A4 ENSG00000197122 SRC H. sapiens SDL Slorth 0.968622 View
ENSG00000100644 HIF1A ENSG00000160868 CYP3A4 H. sapiens SDL Slorth 0.968585 View
ENSG00000150991 UBC ENSG00000160868 CYP3A4 H. sapiens SDL Slorth 0.968194 View
ENSG00000080824 HSP90AA1 ENSG00000160868 CYP3A4 H. sapiens SDL Slorth 0.967973 View
ENSG00000123374 CDK2 ENSG00000160868 CYP3A4 H. sapiens SDL Slorth 0.967226 View
ENSG00000100393 EP300 ENSG00000160868 CYP3A4 H. sapiens SDL Slorth 0.966848 View
ENSG00000104365 IKBKB ENSG00000160868 CYP3A4 H. sapiens SDL Slorth 0.965415 View
ENSG00000097007 ABL1 ENSG00000160868 CYP3A4 H. sapiens SDL Slorth 0.964696 View
ENSG00000110395 CBL ENSG00000160868 CYP3A4 H. sapiens SDL Slorth 0.964478 View
ENSG00000005339 CREBBP ENSG00000160868 CYP3A4 H. sapiens SDL Slorth 0.96418 View
ENSG00000160868 CYP3A4 ENSG00000177885 GRB2 H. sapiens SDL Slorth 0.962529 View
ENSG00000113558 SKP1 ENSG00000160868 CYP3A4 H. sapiens SDL Slorth 0.960895 View
ENSG00000096384 HSP90AB1 ENSG00000160868 CYP3A4 H. sapiens SDL Slorth 0.960064 View
ENSG00000149273 RPS3 ENSG00000160868 CYP3A4 H. sapiens SDL Slorth 0.958346 View
ENSG00000100906 NFKBIA ENSG00000160868 CYP3A4 H. sapiens SDL Slorth 0.958036 View
ENSG00000140464 PML ENSG00000160868 CYP3A4 H. sapiens SDL Slorth 0.95554 View
ENSG00000160868 CYP3A4 ENSG00000162385 MAGOH H. sapiens SDL Slorth 0.953346 View
ENSG00000101146 RAE1 ENSG00000160868 CYP3A4 H. sapiens SSL Slorth 0.9529 View
ENSG00000141646 SMAD4 ENSG00000160868 CYP3A4 H. sapiens SDL Slorth 0.947397 View
ENSG00000097046 CDC7 ENSG00000160868 CYP3A4 H. sapiens SSL Slorth 0.944012 View
ENSG00000135486 HNRNPA1 ENSG00000160868 CYP3A4 H. sapiens SSL Slorth 0.94181 View
ENSG00000160868 CYP3A4 ENSG00000196591 HDAC2 H. sapiens SDL Slorth 0.941784 View
ENSG00000139687 RB1 ENSG00000160868 CYP3A4 H. sapiens SDL Slorth 0.941268 View
ENSG00000109971 HSPA8 ENSG00000160868 CYP3A4 H. sapiens SDL Slorth 0.939036 View
ENSG00000100028 SNRPD3 ENSG00000160868 CYP3A4 H. sapiens SDL Slorth 0.938662 View
ENSG00000136997 MYC ENSG00000160868 CYP3A4 H. sapiens SDL Slorth 0.938412 View