HDAC6

ENSG00000094631 - H. sapiens

Pathways

Go term Description
GO:0001047 core promoter binding
GO:0003779 actin binding
GO:0004407 histone deacetylase activity
GO:0005515 protein binding
GO:0008013 beta-catenin binding
GO:0008017 microtubule binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0031593 polyubiquitin binding
GO:0031625 ubiquitin protein ligase binding
GO:0032041 NAD-dependent histone deacetylase activity (H3-K14 specific)
GO:0042826 histone deacetylase binding
GO:0042903 tubulin deacetylase activity
GO:0043014 alpha-tubulin binding
GO:0048156 tau protein binding
GO:0048487 beta-tubulin binding
GO:0051787 misfolded protein binding
GO:0051879 Hsp90 protein binding
GO:0070840 dynein complex binding
GO:0019213 deacetylase activity

Drugs

Drug name Description
BELINOSTAT Histone deacetylase inhibitor
PANOBINOSTAT Histone deacetylase inhibitor
ROMIDEPSIN Histone deacetylase inhibitor
VORINOSTAT Histone deacetylase 3 inhibitor

Diseases

No diseases in record

Orthologs

Gene Organism
HDA1 S. cerevisiae
hda-6 C. elegans
HDAC6 D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000094631 HDAC6 ENSG00000121879 PIK3CA H. sapiens SSL BioGRID 1.0 View
ENSG00000139618 BRCA2 ENSG00000094631 HDAC6 H. sapiens SSL BioGRID 1.0 View
ENSG00000094631 HDAC6 ENSG00000140443 IGF1R H. sapiens SSL BioGRID 1.0 View
ENSG00000094631 HDAC6 ENSG00000126012 KDM5C H. sapiens SSL BioGRID 1.0 View
ENSG00000094631 HDAC6 ENSG00000163939 PBRM1 H. sapiens SSL BioGRID 1.0 View
ENSG00000070831 CDC42 ENSG00000094631 HDAC6 H. sapiens SDL Slorth 0.985624 View
ENSG00000067560 RHOA ENSG00000094631 HDAC6 H. sapiens SDL Slorth 0.982013 View
ENSG00000091831 ESR1 ENSG00000094631 HDAC6 H. sapiens SDL Slorth 0.981928 View
ENSG00000077782 FGFR1 ENSG00000094631 HDAC6 H. sapiens SDL Slorth 0.981142 View
ENSG00000012048 BRCA1 ENSG00000094631 HDAC6 H. sapiens SDL Slorth 0.980779 View
ENSG00000080824 HSP90AA1 ENSG00000094631 HDAC6 H. sapiens SDL Slorth 0.980391 View
ENSG00000005339 CREBBP ENSG00000094631 HDAC6 H. sapiens SDL Slorth 0.979951 View
ENSG00000094631 HDAC6 ENSG00000133703 KRAS H. sapiens SSL Slorth 0.978012 View
ENSG00000079999 KEAP1 ENSG00000094631 HDAC6 H. sapiens SDL Slorth 0.977867 View
ENSG00000055130 CUL1 ENSG00000094631 HDAC6 H. sapiens SDL Slorth 0.977252 View
ENSG00000082701 GSK3B ENSG00000094631 HDAC6 H. sapiens SDL Slorth 0.975145 View
ENSG00000094631 HDAC6 ENSG00000169083 AR H. sapiens SDL Slorth 0.975028 View
ENSG00000094631 HDAC6 ENSG00000168610 STAT3 H. sapiens SDL Slorth 0.974679 View
ENSG00000069869 NEDD4 ENSG00000094631 HDAC6 H. sapiens SDL Slorth 0.974624 View
ENSG00000094631 HDAC6 ENSG00000142208 AKT1 H. sapiens SDL Slorth 0.973914 View
ENSG00000085733 CTTN ENSG00000094631 HDAC6 H. sapiens SDL Slorth 0.973852 View
ENSG00000010810 FYN ENSG00000094631 HDAC6 H. sapiens SDL Slorth 0.973714 View
ENSG00000094631 HDAC6 ENSG00000177885 GRB2 H. sapiens SDL Slorth 0.97351 View
ENSG00000094631 HDAC6 ENSG00000168036 CTNNB1 H. sapiens SDL Slorth 0.973154 View
ENSG00000094631 HDAC6 ENSG00000185591 SP1 H. sapiens SDL Slorth 0.972959 View
ENSG00000094631 HDAC6 ENSG00000197122 SRC H. sapiens SDL Slorth 0.97294 View
ENSG00000036257 CUL3 ENSG00000094631 HDAC6 H. sapiens SDL Slorth 0.972326 View
ENSG00000082898 XPO1 ENSG00000094631 HDAC6 H. sapiens SDL Slorth 0.971588 View
ENSG00000094631 HDAC6 ENSG00000110395 CBL H. sapiens SDL Slorth 0.971203 View
ENSG00000094631 HDAC6 ENSG00000116478 HDAC1 H. sapiens SDL Slorth 0.97078 View
ENSG00000094631 HDAC6 ENSG00000136997 MYC H. sapiens SDL Slorth 0.970574 View
ENSG00000087191 PSMC5 ENSG00000094631 HDAC6 H. sapiens SDL Slorth 0.970219 View
ENSG00000094631 HDAC6 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.969439 View
ENSG00000094631 HDAC6 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.969421 View
ENSG00000078747 ITCH ENSG00000094631 HDAC6 H. sapiens SDL Slorth 0.96913 View
ENSG00000094631 HDAC6 ENSG00000146648 EGFR H. sapiens SDL Slorth 0.969106 View
ENSG00000094631 HDAC6 ENSG00000100393 EP300 H. sapiens SDL Slorth 0.968858 View
ENSG00000072803 FBXW11 ENSG00000094631 HDAC6 H. sapiens SDL Slorth 0.96868 View
ENSG00000073584 SMARCE1 ENSG00000094631 HDAC6 H. sapiens SDL Slorth 0.968558 View
ENSG00000041357 PSMA4 ENSG00000094631 HDAC6 H. sapiens SDL Slorth 0.968317 View