Go term | Description |
---|---|
GO:0004674 | protein serine/threonine kinase activity |
GO:0004702 | signal transducer, downstream of receptor, with serine/threonine kinase activity |
GO:0004708 | MAP kinase kinase activity |
GO:0004712 | protein serine/threonine/tyrosine kinase activity |
GO:0004713 | protein tyrosine kinase activity |
GO:0005515 | protein binding |
GO:0005524 | ATP binding |
GO:0030165 | PDZ domain binding |
GO:0043539 | protein serine/threonine kinase activator activity |
GO:0046872 | metal ion binding |
GO:0097110 | scaffold protein binding |
Drug name | Description |
---|---|
TRAMETINIB | Dual specificity mitogen-activated protein kinase kinase 2 inhibitor |
Disease Name |
---|
NSCLC |
melanoma |
Gene | Organism | |
---|---|---|
PBS2 | S. cerevisiae | |
mek-2 | C. elegans | |
Dsor1 | D. melanogaster |
Gene ID A | Gene Name A | Gene ID B | Gene Symbol B | Organism | Source | Score? | ||
---|---|---|---|---|---|---|---|---|
ENSG00000126934 | MAP2K2 | ENSG00000128052 | KDR | H. sapiens | SSL | Slorth | 0.806202 | View |
ENSG00000115524 | SF3B1 | ENSG00000126934 | MAP2K2 | H. sapiens | SSL | Slorth | 0.805416 | View |
ENSG00000126934 | MAP2K2 | ENSG00000154229 | PRKCA | H. sapiens | SSL | Slorth | 0.805246 | View |
ENSG00000126934 | MAP2K2 | ENSG00000196470 | SIAH1 | H. sapiens | SSL | Slorth | 0.803213 | View |
ENSG00000126934 | MAP2K2 | ENSG00000150093 | ITGB1 | H. sapiens | SSL | Slorth | 0.797657 | View |
ENSG00000084774 | CAD | ENSG00000126934 | MAP2K2 | H. sapiens | SSL | Slorth | 0.795345 | View |
ENSG00000119048 | UBE2B | ENSG00000126934 | MAP2K2 | H. sapiens | SSL | Slorth | 0.795163 | View |
ENSG00000085832 | EPS15 | ENSG00000126934 | MAP2K2 | H. sapiens | SSL | Slorth | 0.795037 | View |
ENSG00000099817 | POLR2E | ENSG00000126934 | MAP2K2 | H. sapiens | SSL | Slorth | 0.791352 | View |
ENSG00000103126 | AXIN1 | ENSG00000126934 | MAP2K2 | H. sapiens | SSL | Slorth | 0.790988 | View |
ENSG00000126934 | MAP2K2 | ENSG00000165416 | SUGT1 | H. sapiens | SSL | Slorth | 0.789417 | View |
ENSG00000126934 | MAP2K2 | ENSG00000147010 | SH3KBP1 | H. sapiens | SSL | Slorth | 0.789244 | View |
ENSG00000126934 | MAP2K2 | ENSG00000150459 | SAP18 | H. sapiens | SSL | Slorth | 0.788461 | View |
ENSG00000126934 | MAP2K2 | ENSG00000141968 | VAV1 | H. sapiens | SSL | Slorth | 0.787685 | View |
ENSG00000116288 | PARK7 | ENSG00000126934 | MAP2K2 | H. sapiens | SSL | Slorth | 0.787219 | View |
ENSG00000104695 | PPP2CB | ENSG00000126934 | MAP2K2 | H. sapiens | SSL | Slorth | 0.786303 | View |
ENSG00000126934 | MAP2K2 | ENSG00000156970 | BUB1B | H. sapiens | SSL | Slorth | 0.785836 | View |
ENSG00000126934 | MAP2K2 | ENSG00000145386 | CCNA2 | H. sapiens | SSL | Slorth | 0.783845 | View |
ENSG00000126934 | MAP2K2 | ENSG00000172531 | PPP1CA | H. sapiens | SSL | Slorth | 0.783753 | View |
ENSG00000115816 | CEBPZ | ENSG00000126934 | MAP2K2 | H. sapiens | SSL | Slorth | 0.782177 | View |
ENSG00000072803 | FBXW11 | ENSG00000126934 | MAP2K2 | H. sapiens | SSL | Slorth | 0.780835 | View |
ENSG00000126934 | MAP2K2 | ENSG00000170027 | YWHAG | H. sapiens | SSL | Slorth | 0.78001 | View |
ENSG00000126934 | MAP2K2 | ENSG00000127022 | CANX | H. sapiens | SSL | Slorth | 0.778904 | View |
ENSG00000085840 | ORC1 | ENSG00000126934 | MAP2K2 | H. sapiens | SSL | Slorth | 0.778384 | View |
ENSG00000126934 | MAP2K2 | ENSG00000157764 | BRAF | H. sapiens | SSL | Slorth | 0.778053 | View |
ENSG00000126934 | MAP2K2 | ENSG00000168496 | FEN1 | H. sapiens | SSL | Slorth | 0.776402 | View |
ENSG00000126934 | MAP2K2 | ENSG00000141480 | ARRB2 | H. sapiens | SSL | Slorth | 0.775352 | View |
ENSG00000110330 | BIRC2 | ENSG00000126934 | MAP2K2 | H. sapiens | SSL | Slorth | 0.77491 | View |
ENSG00000126934 | MAP2K2 | ENSG00000186868 | MAPT | H. sapiens | SSL | Slorth | 0.773835 | View |
ENSG00000126934 | MAP2K2 | ENSG00000198793 | MTOR | H. sapiens | SSL | Slorth | 0.773732 | View |
ENSG00000126934 | MAP2K2 | ENSG00000132170 | PPARG | H. sapiens | SSL | Slorth | 0.773527 | View |
ENSG00000102882 | MAPK3 | ENSG00000126934 | MAP2K2 | H. sapiens | SSL | Slorth | 0.769468 | View |
ENSG00000126934 | MAP2K2 | ENSG00000140443 | IGF1R | H. sapiens | SSL | Slorth | 0.769278 | View |
ENSG00000114503 | NCBP2 | ENSG00000126934 | MAP2K2 | H. sapiens | SSL | Slorth | 0.768876 | View |
ENSG00000114062 | UBE3A | ENSG00000126934 | MAP2K2 | H. sapiens | SSL | Slorth | 0.766452 | View |
ENSG00000126934 | MAP2K2 | ENSG00000149311 | ATM | H. sapiens | SSL | Slorth | 0.765738 | View |
ENSG00000116478 | HDAC1 | ENSG00000126934 | MAP2K2 | H. sapiens | SSL | Slorth | 0.765263 | View |
ENSG00000064012 | CASP8 | ENSG00000126934 | MAP2K2 | H. sapiens | SSL | Slorth | 0.764974 | View |
ENSG00000126934 | MAP2K2 | ENSG00000141736 | ERBB2 | H. sapiens | SSL | Slorth | 0.76488 | View |
ENSG00000108953 | YWHAE | ENSG00000126934 | MAP2K2 | H. sapiens | SSL | Slorth | 0.764294 | View |