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Genes
Gene:
Organism:
H. sapiens
S. cerevisiae
S. pombe
D. melanogaster
C. elegans
Type:
SSL
SDL
Quality:
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High Quality Predictions
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Experimentally Validated
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Cancer gene:
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Druggable:
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Gene
Ensembl ID
Organism
Diseases
Drugs
Ontology
Interactions
PDIA4
ENSG00000155660
H. sapiens
protein disulfide isomerase activity
protein binding
...
141
CYP3A4
ENSG00000160868
H. sapiens
COBICISTAT
monooxygenase activity
steroid binding
iron ion binding
...
134
PFKFB3
ENSG00000170525
H. sapiens
6-phosphofructo-2-kinase activity
fructose-2,6-bisphosphate 2-phosphatase activity
ATP binding
...
135
NKX2-5
ENSG00000183072
H. sapiens
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
RNA polymerase II transcription cofactor activity
...
287
KIRREL
ENSG00000183853
H. sapiens
protein binding
myosin binding
...
246
ASXL1
ENSG00000171456
H. sapiens
MDS
CMML
DNA binding
transcription coactivator activity
transcription corepressor activity
...
173
TSPYL1
ENSG00000189241
H. sapiens
enzyme binding
...
102
PTPRF
ENSG00000142949
H. sapiens
protein tyrosine phosphatase activity
transmembrane receptor protein tyrosine phosphatase activity
heparin binding
...
121
CTNND1
ENSG00000198561
H. sapiens
large intestine carcinoma
receptor binding
protein binding
protein kinase binding
...
616
CALM3
ENSG00000160014
H. sapiens
...
45
LRIG1
ENSG00000144749
H. sapiens
...
83
PNPLA2
ENSG00000177666
H. sapiens
lipoprotein lipase activity
triglyceride lipase activity
acylglycerol O-acyltransferase activity
...
99
SLC39A10
ENSG00000196950
H. sapiens
zinc ion transmembrane transporter activity
...
85
CCR4
ENSG00000183813
H. sapiens
adult T-cell leukaemia/lymphoma
chemokine receptor activity
C-C chemokine receptor activity
RNA binding
...
38
TRAPPC12
ENSG00000274891
H. sapiens
endopeptidase activity
endopeptidase activity
protein binding
...
33
SSTR5
ENSG00000162009
H. sapiens
LANREOTIDE
OCTREOTIDE
PASIREOTIDE
somatostatin receptor activity
neuropeptide binding
...
6
THAP3
ENSG00000041988
H. sapiens
DNA binding
protein binding
metal ion binding
...
4
WDR5
ENSG00000196363
H. sapiens
protein binding
histone-lysine N-methyltransferase activity
methylated histone binding
...
5
ZNF574
ENSG00000105732
H. sapiens
DNA binding
metal ion binding
...
33
NDUFB4
ENSG00000065518
H. sapiens
METFORMIN
NADH dehydrogenase (ubiquinone) activity
...
3
TSPO
ENSG00000100300
H. sapiens
androgen binding
protein binding
benzodiazepine receptor activity
...
6
CDC26
ENSG00000176386
H. sapiens
protein binding
ubiquitin-protein transferase activity
...
1
MASP2
ENSG00000009724
H. sapiens
complement component C4b binding
serine-type endopeptidase activity
calcium ion binding
...
3
NDUFA4L2
ENSG00000185633
H. sapiens
METFORMIN
NADH dehydrogenase (ubiquinone) activity
cytochrome-c oxidase activity
...
1
SLC16A8
ENSG00000100156
H. sapiens
monocarboxylic acid transmembrane transporter activity
lactate transmembrane transporter activity
symporter activity
...
3
WDR7
ENSG00000091157
H. sapiens
...
26
TPSAB1
ENSG00000172236
H. sapiens
serine-type endopeptidase activity
protein binding
serine-type peptidase activity
...
10
WDR77
ENSG00000116455
H. sapiens
protein binding
methyl-CpG binding
protein-arginine N-methyltransferase activity
...
5
SNRPG
ENSG00000143977
H. sapiens
protein binding
U1 snRNP binding
RNA binding
...
9
UBE2J1
ENSG00000198833
H. sapiens
ATP binding
ubiquitin protein ligase binding
ubiquitin protein ligase activity
...
132
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