ABL1

ENSG00000097007 - H. sapiens

Pathways

Go term Description
GO:0000287 magnesium ion binding
GO:0003677 DNA binding
GO:0003785 actin monomer binding
GO:0004515 nicotinate-nucleotide adenylyltransferase activity
GO:0004672 protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005080 protein kinase C binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008022 protein C-terminus binding
GO:0017124 SH3 domain binding
GO:0019905 syntaxin binding
GO:0030145 manganese ion binding
GO:0051015 actin filament binding
GO:0051019 mitogen-activated protein kinase binding
GO:0070064 proline-rich region binding
GO:0005102 receptor binding

Drugs

Drug name Description
BOSUTINIB Tyrosine-protein kinase ABL inhibitor
DASATINIB Tyrosine-protein kinase ABL inhibitor
IMATINIB Tyrosine-protein kinase ABL inhibitor
NILOTINIB Tyrosine-protein kinase ABL inhibitor
PONATINIB Tyrosine-protein kinase ABL inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor

Diseases

Disease Name
CML
ALL
T-ALL

Orthologs

Gene Organism
abl-1 C. elegans
Abl D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000097007 ABL1 ENSG00000171435 KSR2 H. sapiens SSL Slorth 0.848687 View
ENSG00000097007 ABL1 ENSG00000168959 GRM5 H. sapiens SSL Slorth 0.848503 View
ENSG00000097007 ABL1 ENSG00000150995 ITPR1 H. sapiens SSL Slorth 0.848453 View
ENSG00000097007 ABL1 ENSG00000100056 DGCR14 H. sapiens SSL Slorth 0.848173 View
ENSG00000097007 ABL1 ENSG00000112658 SRF H. sapiens SSL Slorth 0.847962 View
ENSG00000097007 ABL1 ENSG00000182774 RPS17 H. sapiens SSL Slorth 0.847745 View
ENSG00000097007 ABL1 ENSG00000130699 TAF4 H. sapiens SSL Slorth 0.84771 View
ENSG00000097007 ABL1 ENSG00000165280 VCP H. sapiens SSL Slorth 0.847426 View
ENSG00000097007 ABL1 ENSG00000145216 FIP1L1 H. sapiens SSL Slorth 0.847058 View
ENSG00000097007 ABL1 ENSG00000137996 RTCA H. sapiens SSL Slorth 0.846845 View
ENSG00000097007 ABL1 ENSG00000169016 E2F6 H. sapiens SSL Slorth 0.846829 View
ENSG00000097007 ABL1 ENSG00000157782 CABP1 H. sapiens SSL Slorth 0.846725 View
ENSG00000097007 ABL1 ENSG00000165169 DYNLT3 H. sapiens SSL Slorth 0.846638 View
ENSG00000097007 ABL1 ENSG00000164305 CASP3 H. sapiens SSL Slorth 0.846605 View
ENSG00000097007 ABL1 ENSG00000184967 NOC4L H. sapiens SSL Slorth 0.846529 View
ENSG00000097007 ABL1 ENSG00000170312 CDK1 H. sapiens SSL Slorth 0.84642 View
ENSG00000097007 ABL1 ENSG00000139687 RB1 H. sapiens SSL Slorth 0.846146 View
ENSG00000010810 FYN ENSG00000097007 ABL1 H. sapiens SSL Slorth 0.84563 View
ENSG00000097007 ABL1 ENSG00000240682 ISY1 H. sapiens SSL Slorth 0.845211 View
ENSG00000097007 ABL1 ENSG00000163083 INHBB H. sapiens SSL Slorth 0.844971 View
ENSG00000097007 ABL1 ENSG00000137692 DCUN1D5 H. sapiens SSL Slorth 0.844957 View
ENSG00000097007 ABL1 ENSG00000106799 TGFBR1 H. sapiens SSL Slorth 0.844851 View
ENSG00000097007 ABL1 ENSG00000119535 CSF3R H. sapiens SSL Slorth 0.844406 View
ENSG00000097007 ABL1 ENSG00000197769 MAP1LC3C H. sapiens SSL Slorth 0.844021 View
ENSG00000097007 ABL1 ENSG00000108840 HDAC5 H. sapiens SSL Slorth 0.843862 View
ENSG00000097007 ABL1 ENSG00000119396 RAB14 H. sapiens SSL Slorth 0.843842 View
ENSG00000097007 ABL1 ENSG00000111196 MAGOHB H. sapiens SSL Slorth 0.843464 View
ENSG00000097007 ABL1 ENSG00000140307 GTF2A2 H. sapiens SSL Slorth 0.843152 View
ENSG00000097007 ABL1 ENSG00000118058 KMT2A H. sapiens SSL Slorth 0.8428 View
ENSG00000084676 NCOA1 ENSG00000097007 ABL1 H. sapiens SSL Slorth 0.842722 View
ENSG00000097007 ABL1 ENSG00000169083 AR H. sapiens SSL Slorth 0.842502 View
ENSG00000097007 ABL1 ENSG00000134686 PHC2 H. sapiens SSL Slorth 0.842377 View
ENSG00000097007 ABL1 ENSG00000108587 GOSR1 H. sapiens SSL Slorth 0.842274 View
ENSG00000097007 ABL1 ENSG00000126458 RRAS H. sapiens SSL Slorth 0.842077 View
ENSG00000097007 ABL1 ENSG00000147536 GINS4 H. sapiens SSL Slorth 0.841772 View
ENSG00000097007 ABL1 ENSG00000152256 PDK1 H. sapiens SSL Slorth 0.841711 View
ENSG00000097007 ABL1 ENSG00000186184 POLR1D H. sapiens SSL Slorth 0.841662 View
ENSG00000055130 CUL1 ENSG00000097007 ABL1 H. sapiens SSL Slorth 0.841463 View
ENSG00000097007 ABL1 ENSG00000169375 SIN3A H. sapiens SSL Slorth 0.841252 View
ENSG00000097007 ABL1 ENSG00000187266 EPOR H. sapiens SSL Slorth 0.841156 View