ABL1

ENSG00000097007 - H. sapiens

Pathways

Go term Description
GO:0000287 magnesium ion binding
GO:0003677 DNA binding
GO:0003785 actin monomer binding
GO:0004515 nicotinate-nucleotide adenylyltransferase activity
GO:0004672 protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005080 protein kinase C binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008022 protein C-terminus binding
GO:0017124 SH3 domain binding
GO:0019905 syntaxin binding
GO:0030145 manganese ion binding
GO:0051015 actin filament binding
GO:0051019 mitogen-activated protein kinase binding
GO:0070064 proline-rich region binding
GO:0005102 receptor binding

Drugs

Drug name Description
BOSUTINIB Tyrosine-protein kinase ABL inhibitor
DASATINIB Tyrosine-protein kinase ABL inhibitor
IMATINIB Tyrosine-protein kinase ABL inhibitor
NILOTINIB Tyrosine-protein kinase ABL inhibitor
PONATINIB Tyrosine-protein kinase ABL inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor

Diseases

Disease Name
CML
ALL
T-ALL

Orthologs

Gene Organism
abl-1 C. elegans
Abl D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000097007 ABL1 ENSG00000144935 TRPC1 H. sapiens SSL Slorth 0.765281 View
ENSG00000097007 ABL1 ENSG00000104313 EYA1 H. sapiens SSL Slorth 0.764831 View
ENSG00000097007 ABL1 ENSG00000137040 RANBP6 H. sapiens SSL Slorth 0.764766 View
ENSG00000097007 ABL1 ENSG00000165097 KDM1B H. sapiens SSL Slorth 0.764498 View
ENSG00000097007 ABL1 ENSG00000203879 GDI1 H. sapiens SSL Slorth 0.764205 View
ENSG00000097007 ABL1 ENSG00000128626 MRPS12 H. sapiens SSL Slorth 0.763805 View
ENSG00000097007 ABL1 ENSG00000115685 PPP1R7 H. sapiens SSL Slorth 0.763575 View
ENSG00000097007 ABL1 ENSG00000147130 ZMYM3 H. sapiens SSL Slorth 0.763457 View
ENSG00000097007 ABL1 ENSG00000104643 MTMR9 H. sapiens SSL Slorth 0.762712 View
ENSG00000097007 ABL1 ENSG00000173540 GMPPB H. sapiens SSL Slorth 0.762664 View
ENSG00000097007 ABL1 ENSG00000169021 UQCRFS1 H. sapiens SSL Slorth 0.762615 View
ENSG00000097007 ABL1 ENSG00000116830 TTF2 H. sapiens SSL Slorth 0.761147 View
ENSG00000097007 ABL1 ENSG00000133884 DPF2 H. sapiens SSL Slorth 0.76074 View
ENSG00000097007 ABL1 ENSG00000103051 COG4 H. sapiens SSL Slorth 0.760666 View
ENSG00000097007 ABL1 ENSG00000100603 SNW1 H. sapiens SSL Slorth 0.760581 View
ENSG00000085733 CTTN ENSG00000097007 ABL1 H. sapiens SSL Slorth 0.760318 View
ENSG00000097007 ABL1 ENSG00000132849 PATJ H. sapiens SSL Slorth 0.759884 View
ENSG00000079134 THOC1 ENSG00000097007 ABL1 H. sapiens SSL Slorth 0.759709 View
ENSG00000097007 ABL1 ENSG00000169696 ASPSCR1 H. sapiens SSL Slorth 0.759641 View
ENSG00000097007 ABL1 ENSG00000102030 NAA10 H. sapiens SSL Slorth 0.758551 View
ENSG00000097007 ABL1 ENSG00000125257 ABCC4 H. sapiens SSL Slorth 0.758249 View
ENSG00000097007 ABL1 ENSG00000114757 PEX5L H. sapiens SSL Slorth 0.757826 View
ENSG00000097007 ABL1 ENSG00000102172 SMS H. sapiens SSL Slorth 0.757818 View
ENSG00000097007 ABL1 ENSG00000198033 TUBA3C H. sapiens SSL Slorth 0.757504 View
ENSG00000097007 ABL1 ENSG00000126267 COX6B1 H. sapiens SSL Slorth 0.757445 View
ENSG00000097007 ABL1 ENSG00000136238 RAC1 H. sapiens SSL Slorth 0.756267 View
ENSG00000097007 ABL1 ENSG00000198841 KTI12 H. sapiens SSL Slorth 0.756108 View
ENSG00000097007 ABL1 ENSG00000175899 A2M H. sapiens SSL Slorth 0.756105 View
ENSG00000097007 ABL1 ENSG00000101162 TUBB1 H. sapiens SSL Slorth 0.755922 View
ENSG00000097007 ABL1 ENSG00000100347 SAMM50 H. sapiens SSL Slorth 0.755694 View
ENSG00000097007 ABL1 ENSG00000138696 BMPR1B H. sapiens SSL Slorth 0.755567 View
ENSG00000097007 ABL1 ENSG00000163577 EIF5A2 H. sapiens SSL Slorth 0.755263 View
ENSG00000097007 ABL1 ENSG00000198399 ITSN2 H. sapiens SSL Slorth 0.755263 View
ENSG00000097007 ABL1 ENSG00000143569 UBAP2L H. sapiens SSL Slorth 0.755263 View
ENSG00000097007 ABL1 ENSG00000167996 FTH1 H. sapiens SSL Slorth 0.754891 View
ENSG00000097007 ABL1 ENSG00000111716 LDHB H. sapiens SSL Slorth 0.754891 View
ENSG00000069399 BCL3 ENSG00000097007 ABL1 H. sapiens SSL Slorth 0.754667 View
ENSG00000097007 ABL1 ENSG00000133103 COG6 H. sapiens SSL Slorth 0.753598 View
ENSG00000097007 ABL1 ENSG00000166803 KIAA0101 H. sapiens SSL Slorth 0.753448 View
ENSG00000097007 ABL1 ENSG00000185513 L3MBTL1 H. sapiens SSL Slorth 0.753436 View