ABL1

ENSG00000097007 - H. sapiens

Pathways

Go term Description
GO:0000287 magnesium ion binding
GO:0003677 DNA binding
GO:0003785 actin monomer binding
GO:0004515 nicotinate-nucleotide adenylyltransferase activity
GO:0004672 protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005080 protein kinase C binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008022 protein C-terminus binding
GO:0017124 SH3 domain binding
GO:0019905 syntaxin binding
GO:0030145 manganese ion binding
GO:0051015 actin filament binding
GO:0051019 mitogen-activated protein kinase binding
GO:0070064 proline-rich region binding
GO:0005102 receptor binding

Drugs

Drug name Description
BOSUTINIB Tyrosine-protein kinase ABL inhibitor
DASATINIB Tyrosine-protein kinase ABL inhibitor
IMATINIB Tyrosine-protein kinase ABL inhibitor
NILOTINIB Tyrosine-protein kinase ABL inhibitor
PONATINIB Tyrosine-protein kinase ABL inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor

Diseases

Disease Name
CML
ALL
T-ALL

Orthologs

Gene Organism
abl-1 C. elegans
Abl D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000047315 POLR2B ENSG00000097007 ABL1 H. sapiens SSL Slorth 0.788692 View
ENSG00000097007 ABL1 ENSG00000179632 MAF1 H. sapiens SSL Slorth 0.788343 View
ENSG00000097007 ABL1 ENSG00000163527 STT3B H. sapiens SSL Slorth 0.788198 View
ENSG00000097007 ABL1 ENSG00000131725 WDR44 H. sapiens SSL Slorth 0.787663 View
ENSG00000097007 ABL1 ENSG00000153107 ANAPC1 H. sapiens SSL Slorth 0.787374 View
ENSG00000097007 ABL1 ENSG00000112531 QKI H. sapiens SSL Slorth 0.787309 View
ENSG00000097007 ABL1 ENSG00000182578 CSF1R H. sapiens SSL Slorth 0.786998 View
ENSG00000097007 ABL1 ENSG00000196396 PTPN1 H. sapiens SSL Slorth 0.786374 View
ENSG00000077097 TOP2B ENSG00000097007 ABL1 H. sapiens SSL Slorth 0.786319 View
ENSG00000097007 ABL1 ENSG00000105656 ELL H. sapiens SSL Slorth 0.785889 View
ENSG00000072401 UBE2D1 ENSG00000097007 ABL1 H. sapiens SSL Slorth 0.785491 View
ENSG00000097007 ABL1 ENSG00000172671 ZFAND4 H. sapiens SSL Slorth 0.78498 View
ENSG00000012048 BRCA1 ENSG00000097007 ABL1 H. sapiens SSL Slorth 0.784424 View
ENSG00000097007 ABL1 ENSG00000137710 RDX H. sapiens SSL Slorth 0.784168 View
ENSG00000097007 ABL1 ENSG00000143556 S100A7 H. sapiens SSL Slorth 0.783782 View
ENSG00000097007 ABL1 ENSG00000204220 PFDN6 H. sapiens SSL Slorth 0.78306 View
ENSG00000097007 ABL1 ENSG00000104881 PPP1R13L H. sapiens SSL Slorth 0.782898 View
ENSG00000097007 ABL1 ENSG00000110075 PPP6R3 H. sapiens SSL Slorth 0.782698 View
ENSG00000097007 ABL1 ENSG00000175324 LSM1 H. sapiens SSL Slorth 0.781956 View
ENSG00000097007 ABL1 ENSG00000157077 ZFYVE9 H. sapiens SSL Slorth 0.781605 View
ENSG00000097007 ABL1 ENSG00000115266 APC2 H. sapiens SSL Slorth 0.781598 View
ENSG00000097007 ABL1 ENSG00000160214 RRP1 H. sapiens SSL Slorth 0.781594 View
ENSG00000097007 ABL1 ENSG00000116106 EPHA4 H. sapiens SSL Slorth 0.7813 View
ENSG00000097007 ABL1 ENSG00000142675 CNKSR1 H. sapiens SSL Slorth 0.781001 View
ENSG00000097007 ABL1 ENSG00000115884 SDC1 H. sapiens SSL Slorth 0.780872 View
ENSG00000005339 CREBBP ENSG00000097007 ABL1 H. sapiens SSL Slorth 0.780103 View
ENSG00000097007 ABL1 ENSG00000110435 PDHX H. sapiens SSL Slorth 0.779974 View
ENSG00000097007 ABL1 ENSG00000119421 NDUFA8 H. sapiens SSL Slorth 0.77987 View
ENSG00000065559 MAP2K4 ENSG00000097007 ABL1 H. sapiens SSL Slorth 0.779735 View
ENSG00000097007 ABL1 ENSG00000113758 DBN1 H. sapiens SSL Slorth 0.779735 View
ENSG00000072310 SREBF1 ENSG00000097007 ABL1 H. sapiens SSL Slorth 0.778657 View
ENSG00000097007 ABL1 ENSG00000241878 PISD H. sapiens SSL Slorth 0.778381 View
ENSG00000097007 ABL1 ENSG00000124164 VAPB H. sapiens SSL Slorth 0.778359 View
ENSG00000097007 ABL1 ENSG00000108039 XPNPEP1 H. sapiens SSL Slorth 0.778348 View
ENSG00000097007 ABL1 ENSG00000184840 TMED9 H. sapiens SSL Slorth 0.778065 View
ENSG00000097007 ABL1 ENSG00000168453 HR H. sapiens SSL Slorth 0.778022 View
ENSG00000097007 ABL1 ENSG00000108590 MED31 H. sapiens SSL Slorth 0.777621 View
ENSG00000097007 ABL1 ENSG00000124380 SNRNP27 H. sapiens SSL Slorth 0.777099 View
ENSG00000097007 ABL1 ENSG00000108733 PEX12 H. sapiens SSL Slorth 0.777007 View
ENSG00000097007 ABL1 ENSG00000130811 EIF3G H. sapiens SSL Slorth 0.777001 View