IGF1R

ENSG00000140443 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0005010 insulin-like growth factor-activated receptor activity
GO:0005158 insulin receptor binding
GO:0005515 protein binding
GO:0005520 insulin-like growth factor binding
GO:0005524 ATP binding
GO:0031994 insulin-like growth factor I binding
GO:0042802 identical protein binding
GO:0043548 phosphatidylinositol 3-kinase binding
GO:0043559 insulin binding
GO:0043560 insulin receptor substrate binding

Drugs

Drug name Description
MECASERMIN Insulin-like growth factor I receptor agonist
MECASERMIN RINFABATE Insulin-like growth factor I receptor agonist

Diseases

No diseases in record

Orthologs

Gene Organism
daf-2 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000140443 IGF1R ENSG00000148400 NOTCH1 H. sapiens SSL Slorth 0.931873 View
ENSG00000140443 IGF1R ENSG00000165731 RET H. sapiens SSL Slorth 0.931785 View
ENSG00000077782 FGFR1 ENSG00000140443 IGF1R H. sapiens SDL Slorth 0.931693 View
ENSG00000092421 SEMA6A ENSG00000140443 IGF1R H. sapiens SDL Slorth 0.931688 View
ENSG00000135624 CCT7 ENSG00000140443 IGF1R H. sapiens SSL Slorth 0.931419 View
ENSG00000080224 EPHA6 ENSG00000140443 IGF1R H. sapiens SDL Slorth 0.931319 View
ENSG00000069869 NEDD4 ENSG00000140443 IGF1R H. sapiens SSL Slorth 0.931316 View
ENSG00000070718 AP3M2 ENSG00000140443 IGF1R H. sapiens SDL Slorth 0.93117 View
ENSG00000125810 CD93 ENSG00000140443 IGF1R H. sapiens SDL Slorth 0.931166 View
ENSG00000101365 IDH3B ENSG00000140443 IGF1R H. sapiens SDL Slorth 0.931136 View
ENSG00000140443 IGF1R ENSG00000182578 CSF1R H. sapiens SDL Slorth 0.931079 View
ENSG00000140443 IGF1R ENSG00000169398 PTK2 H. sapiens SSL Slorth 0.930906 View
ENSG00000007908 SELE ENSG00000140443 IGF1R H. sapiens SDL Slorth 0.930774 View
ENSG00000140443 IGF1R ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.930585 View
ENSG00000140443 IGF1R ENSG00000172531 PPP1CA H. sapiens SSL Slorth 0.930552 View
ENSG00000135341 MAP3K7 ENSG00000140443 IGF1R H. sapiens SSL Slorth 0.930347 View
ENSG00000132466 ANKRD17 ENSG00000140443 IGF1R H. sapiens SDL Slorth 0.93028 View
ENSG00000116473 RAP1A ENSG00000140443 IGF1R H. sapiens SSL Slorth 0.930224 View
ENSG00000105568 PPP2R1A ENSG00000140443 IGF1R H. sapiens SSL Slorth 0.930223 View
ENSG00000105737 GRIK5 ENSG00000140443 IGF1R H. sapiens SDL Slorth 0.930197 View
ENSG00000107581 EIF3A ENSG00000140443 IGF1R H. sapiens SSL Slorth 0.930191 View
ENSG00000139998 RAB15 ENSG00000140443 IGF1R H. sapiens SDL Slorth 0.930105 View
ENSG00000102572 STK24 ENSG00000140443 IGF1R H. sapiens SSL Slorth 0.929964 View
ENSG00000076242 MLH1 ENSG00000140443 IGF1R H. sapiens SSL Slorth 0.929618 View
ENSG00000113240 CLK4 ENSG00000140443 IGF1R H. sapiens SDL Slorth 0.929576 View
ENSG00000116016 EPAS1 ENSG00000140443 IGF1R H. sapiens SSL Slorth 0.929508 View
ENSG00000090889 KIF4A ENSG00000140443 IGF1R H. sapiens SDL Slorth 0.929377 View
ENSG00000140443 IGF1R ENSG00000169047 IRS1 H. sapiens SSL Slorth 0.92935 View
ENSG00000106327 TFR2 ENSG00000140443 IGF1R H. sapiens SDL Slorth 0.92907 View
ENSG00000047315 POLR2B ENSG00000140443 IGF1R H. sapiens SSL Slorth 0.929003 View
ENSG00000140443 IGF1R ENSG00000182866 LCK H. sapiens SSL Slorth 0.928891 View
ENSG00000140443 IGF1R ENSG00000171791 BCL2 H. sapiens SSL Slorth 0.928828 View
ENSG00000115216 NRBP1 ENSG00000140443 IGF1R H. sapiens SDL Slorth 0.928816 View
ENSG00000099785 MARCH2 ENSG00000140443 IGF1R H. sapiens SDL Slorth 0.928516 View
ENSG00000140443 IGF1R ENSG00000141736 ERBB2 H. sapiens SDL Slorth 0.928454 View
ENSG00000105204 DYRK1B ENSG00000140443 IGF1R H. sapiens SDL Slorth 0.928437 View
ENSG00000140443 IGF1R ENSG00000146094 DOK3 H. sapiens SDL Slorth 0.928356 View
ENSG00000107929 LARP4B ENSG00000140443 IGF1R H. sapiens SDL Slorth 0.928341 View
ENSG00000140443 IGF1R ENSG00000175792 RUVBL1 H. sapiens SSL Slorth 0.928281 View
ENSG00000116459 ATP5F1 ENSG00000140443 IGF1R H. sapiens SSL Slorth 0.928204 View