JAK3

ENSG00000105639 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005102 receptor binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0019903 protein phosphatase binding

Drugs

Drug name Description
TOFACITINIB Janus Kinase (JAK) inhibitor

Diseases

Disease Name
acute megakaryocytic leukaemia
ETP ALL

Orthologs

Gene Organism
hop D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000105639 JAK3 ENSG00000185591 SP1 H. sapiens SDL Slorth 0.908491 View
ENSG00000105639 JAK3 ENSG00000149554 CHEK1 H. sapiens SSL Slorth 0.9026 View
ENSG00000105639 JAK3 ENSG00000118503 TNFAIP3 H. sapiens SSL Slorth 0.89769 View
ENSG00000105639 JAK3 ENSG00000187608 ISG15 H. sapiens SSL Slorth 0.897422 View
ENSG00000105639 JAK3 ENSG00000126457 PRMT1 H. sapiens SSL Slorth 0.8931 View
ENSG00000105639 JAK3 ENSG00000106211 HSPB1 H. sapiens SSL Slorth 0.891602 View
ENSG00000101868 POLA1 ENSG00000105639 JAK3 H. sapiens SSL Slorth 0.891347 View
ENSG00000103275 UBE2I ENSG00000105639 JAK3 H. sapiens SSL Slorth 0.889812 View
ENSG00000105639 JAK3 ENSG00000132170 PPARG H. sapiens SSL Slorth 0.889255 View
ENSG00000105639 JAK3 ENSG00000141480 ARRB2 H. sapiens SSL Slorth 0.889069 View
ENSG00000105639 JAK3 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.886877 View
ENSG00000105639 JAK3 ENSG00000108094 CUL2 H. sapiens SSL Slorth 0.882562 View
ENSG00000105639 JAK3 ENSG00000166851 PLK1 H. sapiens SSL Slorth 0.881474 View
ENSG00000105639 JAK3 ENSG00000172531 PPP1CA H. sapiens SSL Slorth 0.880441 View
ENSG00000105639 JAK3 ENSG00000169750 RAC3 H. sapiens SSL Slorth 0.880383 View
ENSG00000012048 BRCA1 ENSG00000105639 JAK3 H. sapiens SSL Slorth 0.879072 View
ENSG00000105639 JAK3 ENSG00000105810 CDK6 H. sapiens SSL Slorth 0.879035 View
ENSG00000105639 JAK3 ENSG00000283094 PTEN H. sapiens SSL Slorth 0.878996 View
ENSG00000105639 JAK3 ENSG00000127445 PIN1 H. sapiens SSL Slorth 0.876821 View
ENSG00000105639 JAK3 ENSG00000197442 MAP3K5 H. sapiens SSL Slorth 0.876139 View
ENSG00000105639 JAK3 ENSG00000164885 CDK5 H. sapiens SSL Slorth 0.875834 View
ENSG00000049759 NEDD4L ENSG00000105639 JAK3 H. sapiens SSL Slorth 0.874501 View
ENSG00000105639 JAK3 ENSG00000114062 UBE3A H. sapiens SSL Slorth 0.872974 View
ENSG00000055130 CUL1 ENSG00000105639 JAK3 H. sapiens SSL Slorth 0.871467 View
ENSG00000105639 JAK3 ENSG00000114423 CBLB H. sapiens SSL Slorth 0.868496 View
ENSG00000105639 JAK3 ENSG00000156970 BUB1B H. sapiens SSL Slorth 0.867971 View
ENSG00000105639 JAK3 ENSG00000158402 CDC25C H. sapiens SSL Slorth 0.867672 View
ENSG00000105639 JAK3 ENSG00000244687 UBE2V1 H. sapiens SSL Slorth 0.867393 View
ENSG00000105639 JAK3 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.867357 View
ENSG00000105639 JAK3 ENSG00000134086 VHL H. sapiens SSL Slorth 0.866649 View
ENSG00000105639 JAK3 ENSG00000141968 VAV1 H. sapiens SSL Slorth 0.866413 View
ENSG00000105639 JAK3 ENSG00000134982 APC H. sapiens SSL Slorth 0.86469 View
ENSG00000105639 JAK3 ENSG00000254087 LYN H. sapiens SSL Slorth 0.864432 View
ENSG00000105639 JAK3 ENSG00000166508 MCM7 H. sapiens SSL Slorth 0.864235 View
ENSG00000105639 JAK3 ENSG00000185359 HGS H. sapiens SSL Slorth 0.862993 View
ENSG00000105639 JAK3 ENSG00000110330 BIRC2 H. sapiens SSL Slorth 0.862159 View
ENSG00000105639 JAK3 ENSG00000170365 SMAD1 H. sapiens SSL Slorth 0.86174 View
ENSG00000105639 JAK3 ENSG00000118689 FOXO3 H. sapiens SSL Slorth 0.859997 View
ENSG00000105639 JAK3 ENSG00000126561 STAT5A H. sapiens SSL Slorth 0.857239 View
ENSG00000105639 JAK3 ENSG00000147010 SH3KBP1 H. sapiens SSL Slorth 0.856294 View