SMAD4

ENSG00000141646 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000987 core promoter proximal region sequence-specific DNA binding
GO:0001076 transcription factor activity, RNA polymerase II transcription factor binding
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0001085 RNA polymerase II transcription factor binding
GO:0003682 chromatin binding
GO:0005515 protein binding
GO:0005518 collagen binding
GO:0030616 transforming growth factor beta receptor, common-partner cytoplasmic mediator activity
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0044212 transcription regulatory region DNA binding
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
GO:0070411 I-SMAD binding
GO:0070412 R-SMAD binding
GO:0000988 transcription factor activity, protein binding
GO:0003677 DNA binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0043565 sequence-specific DNA binding

Drugs

No drugs in record

Diseases

Disease Name
colorectal
pancreatic
small intestine
gastrointestinal polyp

Orthologs

Gene Organism
Med D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000141646 SMAD4 ENSG00000198033 TUBA3C H. sapiens SSL Slorth 0.823924 View
ENSG00000119718 EIF2B2 ENSG00000141646 SMAD4 H. sapiens SSL Slorth 0.823762 View
ENSG00000141646 SMAD4 ENSG00000166913 YWHAB H. sapiens SSL Slorth 0.82374 View
ENSG00000141646 SMAD4 ENSG00000142945 KIF2C H. sapiens SSL Slorth 0.823688 View
ENSG00000141646 SMAD4 ENSG00000152234 ATP5A1 H. sapiens SSL Slorth 0.823094 View
ENSG00000141646 SMAD4 ENSG00000163513 TGFBR2 H. sapiens SSL Slorth 0.82307 View
ENSG00000137076 TLN1 ENSG00000141646 SMAD4 H. sapiens SSL Slorth 0.82259 View
ENSG00000141646 SMAD4 ENSG00000186184 POLR1D H. sapiens SSL Slorth 0.821718 View
ENSG00000136937 NCBP1 ENSG00000141646 SMAD4 H. sapiens SSL Slorth 0.82055 View
ENSG00000141646 SMAD4 ENSG00000145216 FIP1L1 H. sapiens SSL Slorth 0.820405 View
ENSG00000141646 SMAD4 ENSG00000204120 GIGYF2 H. sapiens SSL Slorth 0.820141 View
ENSG00000141646 SMAD4 ENSG00000156475 PPP2R2B H. sapiens SSL Slorth 0.820079 View
ENSG00000141646 SMAD4 ENSG00000145740 SLC30A5 H. sapiens SSL Slorth 0.819659 View
ENSG00000141646 SMAD4 ENSG00000166411 IDH3A H. sapiens SSL Slorth 0.819412 View
ENSG00000141646 SMAD4 ENSG00000156711 MAPK13 H. sapiens SSL Slorth 0.819191 View
ENSG00000141646 SMAD4 ENSG00000145495 MARCH6 H. sapiens SSL Slorth 0.819122 View
ENSG00000141646 SMAD4 ENSG00000143171 RXRG H. sapiens SSL Slorth 0.81846 View
ENSG00000140396 NCOA2 ENSG00000141646 SMAD4 H. sapiens SSL Slorth 0.818348 View
ENSG00000133119 RFC3 ENSG00000141646 SMAD4 H. sapiens SSL Slorth 0.817564 View
ENSG00000141646 SMAD4 ENSG00000184840 TMED9 H. sapiens SSL Slorth 0.817337 View
ENSG00000141646 SMAD4 ENSG00000161638 ITGA5 H. sapiens SSL Slorth 0.816887 View
ENSG00000119335 SET ENSG00000141646 SMAD4 H. sapiens SSL Slorth 0.815906 View
ENSG00000141646 SMAD4 ENSG00000241685 ARPC1A H. sapiens SSL Slorth 0.815682 View
ENSG00000141646 SMAD4 ENSG00000171843 MLLT3 H. sapiens SSL Slorth 0.815655 View
ENSG00000141646 SMAD4 ENSG00000179041 RRS1 H. sapiens SSL Slorth 0.815587 View
ENSG00000124422 USP22 ENSG00000141646 SMAD4 H. sapiens SSL Slorth 0.815194 View
ENSG00000141646 SMAD4 ENSG00000143632 ACTA1 H. sapiens SSL Slorth 0.815057 View
ENSG00000141646 SMAD4 ENSG00000197769 MAP1LC3C H. sapiens SSL Slorth 0.815023 View
ENSG00000141646 SMAD4 ENSG00000171094 ALK H. sapiens SSL Slorth 0.81492 View
ENSG00000141646 SMAD4 ENSG00000165672 PRDX3 H. sapiens SSL Slorth 0.814141 View
ENSG00000065427 KARS ENSG00000141646 SMAD4 H. sapiens SSL Slorth 0.813651 View
ENSG00000141646 SMAD4 ENSG00000197102 DYNC1H1 H. sapiens SSL Slorth 0.813533 View
ENSG00000076242 MLH1 ENSG00000141646 SMAD4 H. sapiens SSL Slorth 0.813017 View
ENSG00000141646 SMAD4 ENSG00000147955 SIGMAR1 H. sapiens SSL Slorth 0.812958 View
ENSG00000069399 BCL3 ENSG00000141646 SMAD4 H. sapiens SSL Slorth 0.812816 View
ENSG00000141646 SMAD4 ENSG00000147130 ZMYM3 H. sapiens SSL Slorth 0.812019 View
ENSG00000141646 SMAD4 ENSG00000240682 ISY1 H. sapiens SSL Slorth 0.811419 View
ENSG00000141646 SMAD4 ENSG00000182944 EWSR1 H. sapiens SSL Slorth 0.811378 View
ENSG00000141646 SMAD4 ENSG00000156802 ATAD2 H. sapiens SSL Slorth 0.81122 View
ENSG00000066654 THUMPD1 ENSG00000141646 SMAD4 H. sapiens SSL Slorth 0.810941 View