SMAD4

ENSG00000141646 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000987 core promoter proximal region sequence-specific DNA binding
GO:0001076 transcription factor activity, RNA polymerase II transcription factor binding
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0001085 RNA polymerase II transcription factor binding
GO:0003682 chromatin binding
GO:0005515 protein binding
GO:0005518 collagen binding
GO:0030616 transforming growth factor beta receptor, common-partner cytoplasmic mediator activity
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0044212 transcription regulatory region DNA binding
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
GO:0070411 I-SMAD binding
GO:0070412 R-SMAD binding
GO:0000988 transcription factor activity, protein binding
GO:0003677 DNA binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0043565 sequence-specific DNA binding

Drugs

No drugs in record

Diseases

Disease Name
colorectal
pancreatic
small intestine
gastrointestinal polyp

Orthologs

Gene Organism
Med D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000141646 SMAD4 ENSG00000169372 CRADD H. sapiens SDL Slorth 0.983911 View
ENSG00000110031 LPXN ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.983893 View
ENSG00000141646 SMAD4 ENSG00000175376 EIF1AD H. sapiens SDL Slorth 0.983878 View
ENSG00000085449 WDFY1 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.983859 View
ENSG00000135597 REPS1 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.983793 View
ENSG00000141646 SMAD4 ENSG00000157168 NRG1 H. sapiens SDL Slorth 0.983787 View
ENSG00000141646 SMAD4 ENSG00000177105 RHOG H. sapiens SDL Slorth 0.983724 View
ENSG00000049323 LTBP1 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.983622 View
ENSG00000105290 APLP1 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.983564 View
ENSG00000061918 GUCY1B3 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.983562 View
ENSG00000102317 RBM3 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.983502 View
ENSG00000123612 ACVR1C ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.983325 View
ENSG00000100982 PCIF1 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.983309 View
ENSG00000141646 SMAD4 ENSG00000205629 LCMT1 H. sapiens SDL Slorth 0.983118 View
ENSG00000141646 SMAD4 ENSG00000175093 SPSB4 H. sapiens SDL Slorth 0.98307 View
ENSG00000141646 SMAD4 ENSG00000171621 SPSB1 H. sapiens SDL Slorth 0.98307 View
ENSG00000066923 STAG3 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.983034 View
ENSG00000070718 AP3M2 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.983025 View
ENSG00000041353 RAB27B ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.982896 View
ENSG00000125810 CD93 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.982896 View
ENSG00000067829 IDH3G ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.982884 View
ENSG00000130561 SAG ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.982884 View
ENSG00000101365 IDH3B ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.982884 View
ENSG00000141646 SMAD4 ENSG00000165671 NSD1 H. sapiens SDL Slorth 0.982772 View
ENSG00000085999 RAD54L ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.982612 View
ENSG00000132669 RIN2 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.982598 View
ENSG00000141646 SMAD4 ENSG00000172367 PDZD3 H. sapiens SDL Slorth 0.982585 View
ENSG00000141646 SMAD4 ENSG00000248333 CDK11B H. sapiens SDL Slorth 0.982542 View
ENSG00000105737 GRIK5 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.982539 View
ENSG00000141646 SMAD4 ENSG00000142945 KIF2C H. sapiens SDL Slorth 0.982369 View
ENSG00000072422 RHOBTB1 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.982349 View
ENSG00000008853 RHOBTB2 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.982349 View
ENSG00000123094 RASSF8 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.982346 View
ENSG00000129245 FXR2 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.982322 View
ENSG00000128271 ADORA2A ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.982313 View
ENSG00000100320 RBFOX2 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.982306 View
ENSG00000137073 UBAP2 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.982286 View
ENSG00000141646 SMAD4 ENSG00000162889 MAPKAPK2 H. sapiens SDL Slorth 0.982102 View
ENSG00000141646 SMAD4 ENSG00000160145 KALRN H. sapiens SDL Slorth 0.982083 View
ENSG00000141646 SMAD4 ENSG00000143556 S100A7 H. sapiens SDL Slorth 0.982008 View