SMAD4

ENSG00000141646 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000987 core promoter proximal region sequence-specific DNA binding
GO:0001076 transcription factor activity, RNA polymerase II transcription factor binding
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0001085 RNA polymerase II transcription factor binding
GO:0003682 chromatin binding
GO:0005515 protein binding
GO:0005518 collagen binding
GO:0030616 transforming growth factor beta receptor, common-partner cytoplasmic mediator activity
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0044212 transcription regulatory region DNA binding
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
GO:0070411 I-SMAD binding
GO:0070412 R-SMAD binding
GO:0000988 transcription factor activity, protein binding
GO:0003677 DNA binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0043565 sequence-specific DNA binding

Drugs

No drugs in record

Diseases

Disease Name
colorectal
pancreatic
small intestine
gastrointestinal polyp

Orthologs

Gene Organism
Med D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000141646 SMAD4 ENSG00000164045 CDC25A H. sapiens SSL Slorth 0.972771 View
ENSG00000141646 SMAD4 ENSG00000184470 TXNRD2 H. sapiens SDL Slorth 0.972723 View
ENSG00000141646 SMAD4 ENSG00000172071 EIF2AK3 H. sapiens SDL Slorth 0.972705 View
ENSG00000070159 PTPN3 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.972669 View
ENSG00000141646 SMAD4 ENSG00000196470 SIAH1 H. sapiens SSL Slorth 0.972663 View
ENSG00000141646 SMAD4 ENSG00000166333 ILK H. sapiens SDL Slorth 0.972637 View
ENSG00000117400 MPL ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.972593 View
ENSG00000141646 SMAD4 ENSG00000173209 AHSA2 H. sapiens SDL Slorth 0.972576 View
ENSG00000141646 SMAD4 ENSG00000155304 HSPA13 H. sapiens SDL Slorth 0.972576 View
ENSG00000141646 SMAD4 ENSG00000170035 UBE2E3 H. sapiens SSL Slorth 0.972556 View
ENSG00000141646 SMAD4 ENSG00000175832 ETV4 H. sapiens SDL Slorth 0.972517 View
ENSG00000097046 CDC7 ENSG00000141646 SMAD4 H. sapiens SSL Slorth 0.972469 View
ENSG00000141646 SMAD4 ENSG00000175592 FOSL1 H. sapiens SDL Slorth 0.972435 View
ENSG00000141646 SMAD4 ENSG00000168488 ATXN2L H. sapiens SDL Slorth 0.972389 View
ENSG00000141646 SMAD4 ENSG00000168209 DDIT4 H. sapiens SDL Slorth 0.972346 View
ENSG00000141646 SMAD4 ENSG00000147274 RBMX H. sapiens SSL Slorth 0.972315 View
ENSG00000141646 SMAD4 ENSG00000166192 SENP8 H. sapiens SDL Slorth 0.972292 View
ENSG00000141646 SMAD4 ENSG00000152684 PELO H. sapiens SDL Slorth 0.972266 View
ENSG00000141646 SMAD4 ENSG00000196586 MYO6 H. sapiens SDL Slorth 0.972245 View
ENSG00000141646 SMAD4 ENSG00000205531 NAP1L4 H. sapiens SSL Slorth 0.97224 View
ENSG00000141646 SMAD4 ENSG00000198517 MAFK H. sapiens SDL Slorth 0.972167 View
ENSG00000141646 SMAD4 ENSG00000155090 KLF10 H. sapiens SDL Slorth 0.972128 View
ENSG00000141646 SMAD4 ENSG00000165684 SNAPC4 H. sapiens SDL Slorth 0.972127 View
ENSG00000141646 SMAD4 ENSG00000141738 GRB7 H. sapiens SDL Slorth 0.972058 View
ENSG00000141646 SMAD4 ENSG00000169047 IRS1 H. sapiens SSL Slorth 0.972048 View
ENSG00000141646 SMAD4 ENSG00000187098 MITF H. sapiens SDL Slorth 0.972047 View
ENSG00000089159 PXN ENSG00000141646 SMAD4 H. sapiens SSL Slorth 0.972045 View
ENSG00000141646 SMAD4 ENSG00000198492 YTHDF2 H. sapiens SDL Slorth 0.972038 View
ENSG00000141646 SMAD4 ENSG00000162616 DNAJB4 H. sapiens SDL Slorth 0.972038 View
ENSG00000141646 SMAD4 ENSG00000149187 CELF1 H. sapiens SDL Slorth 0.972038 View
ENSG00000141646 SMAD4 ENSG00000163349 HIPK1 H. sapiens SDL Slorth 0.972038 View
ENSG00000141646 SMAD4 ENSG00000157954 WIPI2 H. sapiens SDL Slorth 0.972038 View
ENSG00000141646 SMAD4 ENSG00000160752 FDPS H. sapiens SDL Slorth 0.972038 View
ENSG00000110330 BIRC2 ENSG00000141646 SMAD4 H. sapiens SSL Slorth 0.972022 View
ENSG00000004700 RECQL ENSG00000141646 SMAD4 H. sapiens SSL Slorth 0.972009 View
ENSG00000106327 TFR2 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.971923 View
ENSG00000140564 FURIN ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.971864 View
ENSG00000139219 COL2A1 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.971864 View
ENSG00000087274 ADD1 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.97183 View
ENSG00000141646 SMAD4 ENSG00000150907 FOXO1 H. sapiens SSL Slorth 0.971827 View