SMAD4

ENSG00000141646 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000987 core promoter proximal region sequence-specific DNA binding
GO:0001076 transcription factor activity, RNA polymerase II transcription factor binding
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0001085 RNA polymerase II transcription factor binding
GO:0003682 chromatin binding
GO:0005515 protein binding
GO:0005518 collagen binding
GO:0030616 transforming growth factor beta receptor, common-partner cytoplasmic mediator activity
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0044212 transcription regulatory region DNA binding
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
GO:0070411 I-SMAD binding
GO:0070412 R-SMAD binding
GO:0000988 transcription factor activity, protein binding
GO:0003677 DNA binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0043565 sequence-specific DNA binding

Drugs

No drugs in record

Diseases

Disease Name
colorectal
pancreatic
small intestine
gastrointestinal polyp

Orthologs

Gene Organism
Med D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000141646 SMAD4 ENSG00000213672 NCKIPSD H. sapiens SDL Slorth 0.974455 View
ENSG00000141646 SMAD4 ENSG00000185359 HGS H. sapiens SSL Slorth 0.974402 View
ENSG00000141646 SMAD4 ENSG00000169554 ZEB2 H. sapiens SDL Slorth 0.97437 View
ENSG00000141646 SMAD4 ENSG00000214517 PPME1 H. sapiens SDL Slorth 0.974368 View
ENSG00000141646 SMAD4 ENSG00000196923 PDLIM7 H. sapiens SDL Slorth 0.974351 View
ENSG00000135486 HNRNPA1 ENSG00000141646 SMAD4 H. sapiens SSL Slorth 0.974339 View
ENSG00000099365 STX1B ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.974271 View
ENSG00000141646 SMAD4 ENSG00000170004 CHD3 H. sapiens SSL Slorth 0.974194 View
ENSG00000141646 SMAD4 ENSG00000169891 REPS2 H. sapiens SDL Slorth 0.974183 View
ENSG00000141646 SMAD4 ENSG00000213949 ITGA1 H. sapiens SDL Slorth 0.974155 View
ENSG00000141646 SMAD4 ENSG00000163932 PRKCD H. sapiens SSL Slorth 0.974114 View
ENSG00000141646 SMAD4 ENSG00000173473 SMARCC1 H. sapiens SSL Slorth 0.974111 View
ENSG00000074219 TEAD2 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.974104 View
ENSG00000141646 SMAD4 ENSG00000182606 TRAK1 H. sapiens SDL Slorth 0.974066 View
ENSG00000141646 SMAD4 ENSG00000168453 HR H. sapiens SDL Slorth 0.974061 View
ENSG00000141646 SMAD4 ENSG00000214102 WEE2 H. sapiens SDL Slorth 0.973994 View
ENSG00000092421 SEMA6A ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.973877 View
ENSG00000141646 SMAD4 ENSG00000158022 TRIM63 H. sapiens SDL Slorth 0.973877 View
ENSG00000141646 SMAD4 ENSG00000188021 UBQLN2 H. sapiens SSL Slorth 0.973835 View
ENSG00000141646 SMAD4 ENSG00000198648 STK39 H. sapiens SDL Slorth 0.973772 View
ENSG00000141646 SMAD4 ENSG00000169032 MAP2K1 H. sapiens SDL Slorth 0.97374 View
ENSG00000141646 SMAD4 ENSG00000168283 BMI1 H. sapiens SDL Slorth 0.973712 View
ENSG00000141646 SMAD4 ENSG00000165304 MELK H. sapiens SDL Slorth 0.973631 View
ENSG00000141646 SMAD4 ENSG00000158402 CDC25C H. sapiens SSL Slorth 0.973623 View
ENSG00000101868 POLA1 ENSG00000141646 SMAD4 H. sapiens SSL Slorth 0.973487 View
ENSG00000134086 VHL ENSG00000141646 SMAD4 H. sapiens SSL Slorth 0.973427 View
ENSG00000141646 SMAD4 ENSG00000169045 HNRNPH1 H. sapiens SSL Slorth 0.973329 View
ENSG00000141646 SMAD4 ENSG00000150459 SAP18 H. sapiens SSL Slorth 0.973321 View
ENSG00000141646 SMAD4 ENSG00000196911 KPNA5 H. sapiens SDL Slorth 0.973261 View
ENSG00000110148 CCKBR ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.973174 View
ENSG00000141646 SMAD4 ENSG00000157456 CCNB2 H. sapiens SDL Slorth 0.97317 View
ENSG00000132646 PCNA ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.973138 View
ENSG00000141646 SMAD4 ENSG00000173801 JUP H. sapiens SDL Slorth 0.97308 View
ENSG00000141646 SMAD4 ENSG00000166477 LEO1 H. sapiens SDL Slorth 0.972902 View
ENSG00000089250 NOS1 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.972888 View
ENSG00000141646 SMAD4 ENSG00000188603 CLN3 H. sapiens SDL Slorth 0.972871 View
ENSG00000011454 RABGAP1 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.972839 View
ENSG00000141646 SMAD4 ENSG00000172175 MALT1 H. sapiens SDL Slorth 0.972837 View
ENSG00000140455 USP3 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.97281 View
ENSG00000141646 SMAD4 ENSG00000167986 DDB1 H. sapiens SSL Slorth 0.97278 View