SMAD4

ENSG00000141646 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000987 core promoter proximal region sequence-specific DNA binding
GO:0001076 transcription factor activity, RNA polymerase II transcription factor binding
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0001085 RNA polymerase II transcription factor binding
GO:0003682 chromatin binding
GO:0005515 protein binding
GO:0005518 collagen binding
GO:0030616 transforming growth factor beta receptor, common-partner cytoplasmic mediator activity
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0044212 transcription regulatory region DNA binding
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
GO:0070411 I-SMAD binding
GO:0070412 R-SMAD binding
GO:0000988 transcription factor activity, protein binding
GO:0003677 DNA binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0043565 sequence-specific DNA binding

Drugs

No drugs in record

Diseases

Disease Name
colorectal
pancreatic
small intestine
gastrointestinal polyp

Orthologs

Gene Organism
Med D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000141646 SMAD4 ENSG00000170242 USP47 H. sapiens SDL Slorth 0.981793 View
ENSG00000100852 ARHGAP5 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.98156 View
ENSG00000141646 SMAD4 ENSG00000173334 TRIB1 H. sapiens SDL Slorth 0.98144 View
ENSG00000077279 DCX ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.981348 View
ENSG00000141646 SMAD4 ENSG00000155849 ELMO1 H. sapiens SDL Slorth 0.981347 View
ENSG00000082146 STRADB ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.981345 View
ENSG00000101134 DOK5 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.98134 View
ENSG00000136237 RAPGEF5 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.981316 View
ENSG00000139998 RAB15 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.981309 View
ENSG00000137825 ITPKA ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.981285 View
ENSG00000111540 RAB5B ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.981248 View
ENSG00000111262 KCNA1 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.981186 View
ENSG00000078114 NEBL ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.981182 View
ENSG00000108830 RND2 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.98112 View
ENSG00000137942 FNBP1L ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.981002 View
ENSG00000137166 FOXP4 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.980946 View
ENSG00000072163 LIMS2 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.980942 View
ENSG00000135312 HTR1B ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.980901 View
ENSG00000140750 ARHGAP17 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.980901 View
ENSG00000072315 TRPC5 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.980901 View
ENSG00000141646 SMAD4 ENSG00000169862 CTNND2 H. sapiens SDL Slorth 0.980838 View
ENSG00000135776 ABCB10 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.980708 View
ENSG00000079335 CDC14A ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.980645 View
ENSG00000007264 MATK ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.98064 View
ENSG00000141646 SMAD4 ENSG00000180176 TH H. sapiens SDL Slorth 0.980597 View
ENSG00000029639 TFB1M ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.980595 View
ENSG00000141646 SMAD4 ENSG00000196218 RYR1 H. sapiens SDL Slorth 0.980511 View
ENSG00000075340 ADD2 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.980442 View
ENSG00000141646 SMAD4 ENSG00000152104 PTPN14 H. sapiens SDL Slorth 0.980422 View
ENSG00000141646 SMAD4 ENSG00000180900 SCRIB H. sapiens SDL Slorth 0.98031 View
ENSG00000141646 SMAD4 ENSG00000187522 HSPA14 H. sapiens SDL Slorth 0.980259 View
ENSG00000141646 SMAD4 ENSG00000165506 DNAAF2 H. sapiens SDL Slorth 0.980259 View
ENSG00000141646 SMAD4 ENSG00000149930 TAOK2 H. sapiens SDL Slorth 0.98023 View
ENSG00000141646 SMAD4 ENSG00000169926 KLF13 H. sapiens SDL Slorth 0.980131 View
ENSG00000041982 TNC ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.980127 View
ENSG00000141646 SMAD4 ENSG00000188130 MAPK12 H. sapiens SDL Slorth 0.980067 View
ENSG00000141646 SMAD4 ENSG00000162775 RBM15 H. sapiens SDL Slorth 0.980061 View
ENSG00000133124 IRS4 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.979985 View
ENSG00000141646 SMAD4 ENSG00000221829 FANCG H. sapiens SDL Slorth 0.979956 View
ENSG00000141646 SMAD4 ENSG00000204390 HSPA1L H. sapiens SDL Slorth 0.979955 View