SMAD4

ENSG00000141646 - H. sapiens

Pathways

Go term Description
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000987 core promoter proximal region sequence-specific DNA binding
GO:0001076 transcription factor activity, RNA polymerase II transcription factor binding
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0001085 RNA polymerase II transcription factor binding
GO:0003682 chromatin binding
GO:0005515 protein binding
GO:0005518 collagen binding
GO:0030616 transforming growth factor beta receptor, common-partner cytoplasmic mediator activity
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0044212 transcription regulatory region DNA binding
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
GO:0070411 I-SMAD binding
GO:0070412 R-SMAD binding
GO:0000988 transcription factor activity, protein binding
GO:0003677 DNA binding
GO:0003700 transcription factor activity, sequence-specific DNA binding
GO:0043565 sequence-specific DNA binding

Drugs

No drugs in record

Diseases

Disease Name
colorectal
pancreatic
small intestine
gastrointestinal polyp

Orthologs

Gene Organism
Med D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000141646 SMAD4 ENSG00000187555 USP7 H. sapiens SSL Slorth 0.978558 View
ENSG00000141646 SMAD4 ENSG00000165115 KIF27 H. sapiens SDL Slorth 0.97853 View
ENSG00000141646 SMAD4 ENSG00000154447 SH3RF1 H. sapiens SDL Slorth 0.978511 View
ENSG00000141646 SMAD4 ENSG00000169714 CNBP H. sapiens SDL Slorth 0.978491 View
ENSG00000141646 SMAD4 ENSG00000198353 HOXC4 H. sapiens SDL Slorth 0.978476 View
ENSG00000141646 SMAD4 ENSG00000155366 RHOC H. sapiens SDL Slorth 0.978467 View
ENSG00000141646 SMAD4 ENSG00000156299 TIAM1 H. sapiens SDL Slorth 0.978325 View
ENSG00000141646 SMAD4 ENSG00000175793 SFN H. sapiens SSL Slorth 0.978257 View
ENSG00000141646 SMAD4 ENSG00000188191 PRKAR1B H. sapiens SDL Slorth 0.978256 View
ENSG00000079432 CIC ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.978209 View
ENSG00000141646 SMAD4 ENSG00000188486 H2AFX H. sapiens SSL Slorth 0.978021 View
ENSG00000141646 SMAD4 ENSG00000198838 RYR3 H. sapiens SDL Slorth 0.978013 View
ENSG00000141646 SMAD4 ENSG00000188906 LRRK2 H. sapiens SSL Slorth 0.978012 View
ENSG00000141646 SMAD4 ENSG00000196914 ARHGEF12 H. sapiens SDL Slorth 0.977927 View
ENSG00000141646 SMAD4 ENSG00000143867 OSR1 H. sapiens SDL Slorth 0.977864 View
ENSG00000141646 SMAD4 ENSG00000169800 RBMY1F H. sapiens SDL Slorth 0.977837 View
ENSG00000112679 DUSP22 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.977821 View
ENSG00000141646 SMAD4 ENSG00000147130 ZMYM3 H. sapiens SDL Slorth 0.977817 View
ENSG00000008196 TFAP2B ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.977765 View
ENSG00000012048 BRCA1 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.977732 View
ENSG00000123600 METTL8 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.977704 View
ENSG00000141646 SMAD4 ENSG00000145386 CCNA2 H. sapiens SSL Slorth 0.977547 View
ENSG00000141646 SMAD4 ENSG00000167996 FTH1 H. sapiens SDL Slorth 0.977535 View
ENSG00000141646 SMAD4 ENSG00000206181 TCEB3B H. sapiens SDL Slorth 0.977517 View
ENSG00000141646 SMAD4 ENSG00000182968 SOX1 H. sapiens SDL Slorth 0.977509 View
ENSG00000141646 SMAD4 ENSG00000165392 WRN H. sapiens SSL Slorth 0.977437 View
ENSG00000141646 SMAD4 ENSG00000151422 FER H. sapiens SDL Slorth 0.977419 View
ENSG00000141646 SMAD4 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.977401 View
ENSG00000141646 SMAD4 ENSG00000197063 MAFG H. sapiens SDL Slorth 0.977384 View
ENSG00000141646 SMAD4 ENSG00000141736 ERBB2 H. sapiens SSL Slorth 0.977354 View
ENSG00000141646 SMAD4 ENSG00000165409 TSHR H. sapiens SDL Slorth 0.977337 View
ENSG00000118900 UBN1 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.977225 View
ENSG00000058404 CAMK2B ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.97721 View
ENSG00000132437 DDC ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.977166 View
ENSG00000141646 SMAD4 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.977134 View
ENSG00000141646 SMAD4 ENSG00000184900 SUMO3 H. sapiens SSL Slorth 0.977109 View
ENSG00000141646 SMAD4 ENSG00000159216 RUNX1 H. sapiens SSL Slorth 0.977109 View
ENSG00000141646 SMAD4 ENSG00000176105 YES1 H. sapiens SDL Slorth 0.977018 View
ENSG00000115221 ITGB6 ENSG00000141646 SMAD4 H. sapiens SDL Slorth 0.977011 View
ENSG00000141646 SMAD4 ENSG00000244687 UBE2V1 H. sapiens SSL Slorth 0.97701 View