ABL1

ENSG00000097007 - H. sapiens

Pathways

Go term Description
GO:0000287 magnesium ion binding
GO:0003677 DNA binding
GO:0003785 actin monomer binding
GO:0004515 nicotinate-nucleotide adenylyltransferase activity
GO:0004672 protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005080 protein kinase C binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008022 protein C-terminus binding
GO:0017124 SH3 domain binding
GO:0019905 syntaxin binding
GO:0030145 manganese ion binding
GO:0051015 actin filament binding
GO:0051019 mitogen-activated protein kinase binding
GO:0070064 proline-rich region binding
GO:0005102 receptor binding

Drugs

Drug name Description
BOSUTINIB Tyrosine-protein kinase ABL inhibitor
DASATINIB Tyrosine-protein kinase ABL inhibitor
IMATINIB Tyrosine-protein kinase ABL inhibitor
NILOTINIB Tyrosine-protein kinase ABL inhibitor
PONATINIB Tyrosine-protein kinase ABL inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor

Diseases

Disease Name
CML
ALL
T-ALL

Orthologs

Gene Organism
abl-1 C. elegans
Abl D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000097007 ABL1 ENSG00000188996 HUS1B H. sapiens SDL Slorth 0.978522 View
ENSG00000097007 ABL1 ENSG00000102225 CDK16 H. sapiens SDL Slorth 0.978519 View
ENSG00000097007 ABL1 ENSG00000134371 CDC73 H. sapiens SDL Slorth 0.978498 View
ENSG00000097007 ABL1 ENSG00000100591 AHSA1 H. sapiens SDL Slorth 0.978488 View
ENSG00000097007 ABL1 ENSG00000114062 UBE3A H. sapiens SDL Slorth 0.978472 View
ENSG00000097007 ABL1 ENSG00000178921 PFAS H. sapiens SDL Slorth 0.97847 View
ENSG00000097007 ABL1 ENSG00000196911 KPNA5 H. sapiens SDL Slorth 0.978462 View
ENSG00000097007 ABL1 ENSG00000169696 ASPSCR1 H. sapiens SDL Slorth 0.978461 View
ENSG00000097007 ABL1 ENSG00000168385 SEPT2 H. sapiens SDL Slorth 0.978446 View
ENSG00000097007 ABL1 ENSG00000124784 RIOK1 H. sapiens SDL Slorth 0.978432 View
ENSG00000097007 ABL1 ENSG00000167004 PDIA3 H. sapiens SDL Slorth 0.978426 View
ENSG00000097007 ABL1 ENSG00000185386 MAPK11 H. sapiens SDL Slorth 0.978413 View
ENSG00000097007 ABL1 ENSG00000122966 CIT H. sapiens SDL Slorth 0.97839 View
ENSG00000097007 ABL1 ENSG00000110422 HIPK3 H. sapiens SDL Slorth 0.978375 View
ENSG00000080561 MID2 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.978354 View
ENSG00000023318 ERP44 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.978333 View
ENSG00000097007 ABL1 ENSG00000183791 TCEB3C H. sapiens SDL Slorth 0.978331 View
ENSG00000097007 ABL1 ENSG00000101310 SEC23B H. sapiens SDL Slorth 0.978313 View
ENSG00000013375 PGM3 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.978311 View
ENSG00000097007 ABL1 ENSG00000126858 RHOT1 H. sapiens SDL Slorth 0.97831 View
ENSG00000097007 ABL1 ENSG00000185513 L3MBTL1 H. sapiens SDL Slorth 0.97831 View
ENSG00000097007 ABL1 ENSG00000171241 SHCBP1 H. sapiens SDL Slorth 0.978294 View
ENSG00000097007 ABL1 ENSG00000160271 RALGDS H. sapiens SDL Slorth 0.978276 View
ENSG00000097007 ABL1 ENSG00000168283 BMI1 H. sapiens SDL Slorth 0.978258 View
ENSG00000097007 ABL1 ENSG00000183337 BCOR H. sapiens SDL Slorth 0.978227 View
ENSG00000097007 ABL1 ENSG00000112701 SENP6 H. sapiens SDL Slorth 0.978226 View
ENSG00000097007 ABL1 ENSG00000196914 ARHGEF12 H. sapiens SDL Slorth 0.978214 View
ENSG00000047849 MAP4 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.978187 View
ENSG00000072134 EPN2 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.978164 View
ENSG00000097007 ABL1 ENSG00000171094 ALK H. sapiens SDL Slorth 0.978157 View
ENSG00000078304 PPP2R5C ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.978133 View
ENSG00000087995 METTL2A ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.978126 View
ENSG00000075426 FOSL2 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.978106 View
ENSG00000097007 ABL1 ENSG00000138468 SENP7 H. sapiens SDL Slorth 0.978104 View
ENSG00000097007 ABL1 ENSG00000175216 CKAP5 H. sapiens SDL Slorth 0.978071 View
ENSG00000097007 ABL1 ENSG00000196262 PPIA H. sapiens SDL Slorth 0.978064 View
ENSG00000097007 ABL1 ENSG00000186871 ERCC6L H. sapiens SDL Slorth 0.978054 View
ENSG00000097007 ABL1 ENSG00000165699 TSC1 H. sapiens SDL Slorth 0.97804 View
ENSG00000097007 ABL1 ENSG00000174437 ATP2A2 H. sapiens SDL Slorth 0.978036 View
ENSG00000097007 ABL1 ENSG00000120833 SOCS2 H. sapiens SDL Slorth 0.977943 View