CDK4

ENSG00000135446 - H. sapiens

Pathways

Go term Description
GO:0004693 cyclin-dependent protein serine/threonine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity
GO:0030332 cyclin binding
GO:0032403 protein complex binding
GO:0004674 protein serine/threonine kinase activity

Drugs

Drug name Description
PALBOCICLIB CDK4/cyclin D1 inhibitor

Diseases

Disease Name
melanoma

Orthologs

Gene Organism
CDC28 S. cerevisiae
cdk-4 C. elegans
Cdk4 D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000135446 CDK4 ENSG00000165115 KIF27 H. sapiens SDL Slorth 0.962074 View
ENSG00000036257 CUL3 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.961969 View
ENSG00000097046 CDC7 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.961947 View
ENSG00000135446 CDK4 ENSG00000188906 LRRK2 H. sapiens SSL Slorth 0.961891 View
ENSG00000077279 DCX ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.961814 View
ENSG00000079999 KEAP1 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.961657 View
ENSG00000135446 CDK4 ENSG00000156299 TIAM1 H. sapiens SDL Slorth 0.961642 View
ENSG00000135446 CDK4 ENSG00000175197 DDIT3 H. sapiens SSL Slorth 0.961615 View
ENSG00000070756 PABPC1 ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.961566 View
ENSG00000135446 CDK4 ENSG00000164109 MAD2L1 H. sapiens SDL Slorth 0.961553 View
ENSG00000135446 CDK4 ENSG00000160224 AIRE H. sapiens SDL Slorth 0.961388 View
ENSG00000135446 CDK4 ENSG00000177606 JUN H. sapiens SSL Slorth 0.96136 View
ENSG00000087586 AURKA ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.961325 View
ENSG00000075624 ACTB ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.961231 View
ENSG00000105173 CCNE1 ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.961118 View
ENSG00000099817 POLR2E ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.961094 View
ENSG00000135446 CDK4 ENSG00000145386 CCNA2 H. sapiens SDL Slorth 0.961077 View
ENSG00000135446 CDK4 ENSG00000185359 HGS H. sapiens SSL Slorth 0.961036 View
ENSG00000108424 KPNB1 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.961001 View
ENSG00000128245 YWHAH ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.960983 View
ENSG00000135446 CDK4 ENSG00000180900 SCRIB H. sapiens SDL Slorth 0.96089 View
ENSG00000135446 CDK4 ENSG00000164885 CDK5 H. sapiens SDL Slorth 0.960863 View
ENSG00000104695 PPP2CB ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.960854 View
ENSG00000135446 CDK4 ENSG00000163098 BIRC8 H. sapiens SDL Slorth 0.960806 View
ENSG00000060069 CTDP1 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.960778 View
ENSG00000135446 CDK4 ENSG00000164885 CDK5 H. sapiens SSL Slorth 0.960742 View
ENSG00000135446 CDK4 ENSG00000143190 POU2F1 H. sapiens SSL Slorth 0.960681 View
ENSG00000135446 CDK4 ENSG00000182511 FES H. sapiens SDL Slorth 0.96066 View
ENSG00000135446 CDK4 ENSG00000186908 ZDHHC17 H. sapiens SDL Slorth 0.960571 View
ENSG00000114062 UBE3A ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.960555 View
ENSG00000135446 CDK4 ENSG00000170312 CDK1 H. sapiens SSL Slorth 0.96055 View
ENSG00000135446 CDK4 ENSG00000142168 SOD1 H. sapiens SDL Slorth 0.960354 View
ENSG00000135446 CDK4 ENSG00000155508 CNOT8 H. sapiens SDL Slorth 0.960269 View
ENSG00000135446 CDK4 ENSG00000186868 MAPT H. sapiens SSL Slorth 0.960128 View
ENSG00000135446 CDK4 ENSG00000136810 TXN H. sapiens SSL Slorth 0.960077 View
ENSG00000135446 CDK4 ENSG00000146648 EGFR H. sapiens SDL Slorth 0.960061 View
ENSG00000096384 HSP90AB1 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.959989 View
ENSG00000135446 CDK4 ENSG00000137843 PAK6 H. sapiens SDL Slorth 0.959603 View
ENSG00000135446 CDK4 ENSG00000143033 MTF2 H. sapiens SDL Slorth 0.959593 View
ENSG00000131747 TOP2A ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.959554 View