FGFR1

ENSG00000077782 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0005007 fibroblast growth factor-activated receptor activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008201 heparin binding
GO:0016303 1-phosphatidylinositol-3-kinase activity
GO:0017134 fibroblast growth factor binding
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity

Drugs

Drug name Description
LENVATINIB
NINTEDANIB Platelet-derived growth factor receptor inhibitor
PAZOPANIB Tyrosine-protein kinase LCK inhibitor
PONATINIB Tyrosine-protein kinase ABL inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor

Diseases

Disease Name
MPN
NHL
salivary adenoma

Orthologs

Gene Organism
egl-15 C. elegans
htl D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000077782 FGFR1 ENSG00000177981 ASB8 H. sapiens SDL Slorth 0.968419 View
ENSG00000077782 FGFR1 ENSG00000116478 HDAC1 H. sapiens SDL Slorth 0.968369 View
ENSG00000077782 FGFR1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.968162 View
ENSG00000077782 FGFR1 ENSG00000198561 CTNND1 H. sapiens SDL Slorth 0.96779 View
ENSG00000077782 FGFR1 ENSG00000171150 SOCS5 H. sapiens SDL Slorth 0.967338 View
ENSG00000077782 FGFR1 ENSG00000155846 PPARGC1B H. sapiens SDL Slorth 0.967293 View
ENSG00000077782 FGFR1 ENSG00000168646 AXIN2 H. sapiens SDL Slorth 0.966824 View
ENSG00000077782 FGFR1 ENSG00000123094 RASSF8 H. sapiens SDL Slorth 0.96674 View
ENSG00000077782 FGFR1 ENSG00000136997 MYC H. sapiens SDL Slorth 0.966714 View
ENSG00000077782 FGFR1 ENSG00000146094 DOK3 H. sapiens SDL Slorth 0.965985 View
ENSG00000077782 FGFR1 ENSG00000185697 MYBL1 H. sapiens SDL Slorth 0.965815 View
ENSG00000077782 FGFR1 ENSG00000141510 TP53 H. sapiens SDL Slorth 0.965355 View
ENSG00000077782 FGFR1 ENSG00000105290 APLP1 H. sapiens SDL Slorth 0.96532 View
ENSG00000077782 FGFR1 ENSG00000178394 HTR1A H. sapiens SDL Slorth 0.964991 View
ENSG00000077782 FGFR1 ENSG00000122966 CIT H. sapiens SDL Slorth 0.964073 View
ENSG00000077782 FGFR1 ENSG00000157168 NRG1 H. sapiens SDL Slorth 0.963763 View
ENSG00000077782 FGFR1 ENSG00000198838 RYR3 H. sapiens SDL Slorth 0.96367 View
ENSG00000077782 FGFR1 ENSG00000197122 SRC H. sapiens SDL Slorth 0.963311 View
ENSG00000021574 SPAST ENSG00000077782 FGFR1 H. sapiens SDL Slorth 0.962974 View
ENSG00000077782 FGFR1 ENSG00000131400 NAPSA H. sapiens SDL Slorth 0.962805 View
ENSG00000077782 FGFR1 ENSG00000154237 LRRK1 H. sapiens SDL Slorth 0.962549 View
ENSG00000077782 FGFR1 ENSG00000160224 AIRE H. sapiens SDL Slorth 0.962231 View
ENSG00000077782 FGFR1 ENSG00000170315 UBB H. sapiens SDL Slorth 0.962146 View
ENSG00000077782 FGFR1 ENSG00000196591 HDAC2 H. sapiens SDL Slorth 0.961844 View
ENSG00000077782 FGFR1 ENSG00000136573 BLK H. sapiens SDL Slorth 0.961809 View
ENSG00000077782 FGFR1 ENSG00000111218 PRMT8 H. sapiens SDL Slorth 0.961551 View
ENSG00000077782 FGFR1 ENSG00000146648 EGFR H. sapiens SDL Slorth 0.960245 View
ENSG00000077782 FGFR1 ENSG00000101266 CSNK2A1 H. sapiens SDL Slorth 0.960079 View
ENSG00000077782 FGFR1 ENSG00000116017 ARID3A H. sapiens SDL Slorth 0.959928 View
ENSG00000069869 NEDD4 ENSG00000077782 FGFR1 H. sapiens SDL Slorth 0.959849 View
ENSG00000077782 FGFR1 ENSG00000119866 BCL11A H. sapiens SDL Slorth 0.959362 View
ENSG00000077782 FGFR1 ENSG00000091831 ESR1 H. sapiens SDL Slorth 0.959126 View
ENSG00000077782 FGFR1 ENSG00000169714 CNBP H. sapiens SDL Slorth 0.958772 View
ENSG00000077782 FGFR1 ENSG00000136021 SCYL2 H. sapiens SDL Slorth 0.958591 View
ENSG00000077782 FGFR1 ENSG00000165671 NSD1 H. sapiens SDL Slorth 0.958153 View
ENSG00000010810 FYN ENSG00000077782 FGFR1 H. sapiens SDL Slorth 0.957753 View
ENSG00000077782 FGFR1 ENSG00000131941 RHPN2 H. sapiens SDL Slorth 0.956741 View
ENSG00000077782 FGFR1 ENSG00000116044 NFE2L2 H. sapiens SDL Slorth 0.95642 View
ENSG00000077782 FGFR1 ENSG00000110395 CBL H. sapiens SDL Slorth 0.956294 View
ENSG00000072163 LIMS2 ENSG00000077782 FGFR1 H. sapiens SDL Slorth 0.956152 View