ABL1

ENSG00000097007 - H. sapiens

Pathways

Go term Description
GO:0000287 magnesium ion binding
GO:0003677 DNA binding
GO:0003785 actin monomer binding
GO:0004515 nicotinate-nucleotide adenylyltransferase activity
GO:0004672 protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005080 protein kinase C binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008022 protein C-terminus binding
GO:0017124 SH3 domain binding
GO:0019905 syntaxin binding
GO:0030145 manganese ion binding
GO:0051015 actin filament binding
GO:0051019 mitogen-activated protein kinase binding
GO:0070064 proline-rich region binding
GO:0005102 receptor binding

Drugs

Drug name Description
BOSUTINIB Tyrosine-protein kinase ABL inhibitor
DASATINIB Tyrosine-protein kinase ABL inhibitor
IMATINIB Tyrosine-protein kinase ABL inhibitor
NILOTINIB Tyrosine-protein kinase ABL inhibitor
PONATINIB Tyrosine-protein kinase ABL inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor

Diseases

Disease Name
CML
ALL
T-ALL

Orthologs

Gene Organism
abl-1 C. elegans
Abl D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000066923 STAG3 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.982544 View
ENSG00000097007 ABL1 ENSG00000169800 RBMY1F H. sapiens SDL Slorth 0.982541 View
ENSG00000274176 CNOT3 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.982541 View
ENSG00000066455 GOLGA5 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.982515 View
ENSG00000097007 ABL1 ENSG00000125818 PSMF1 H. sapiens SDL Slorth 0.982462 View
ENSG00000097007 ABL1 ENSG00000100311 PDGFB H. sapiens SDL Slorth 0.982417 View
ENSG00000097007 ABL1 ENSG00000111859 NEDD9 H. sapiens SDL Slorth 0.982325 View
ENSG00000097007 ABL1 ENSG00000115290 GRB14 H. sapiens SDL Slorth 0.982321 View
ENSG00000021574 SPAST ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.98232 View
ENSG00000097007 ABL1 ENSG00000122691 TWIST1 H. sapiens SDL Slorth 0.98229 View
ENSG00000097007 ABL1 ENSG00000155849 ELMO1 H. sapiens SDL Slorth 0.982247 View
ENSG00000097007 ABL1 ENSG00000165115 KIF27 H. sapiens SDL Slorth 0.982232 View
ENSG00000041353 RAB27B ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.982228 View
ENSG00000097007 ABL1 ENSG00000139719 VPS33A H. sapiens SDL Slorth 0.982198 View
ENSG00000097007 ABL1 ENSG00000129204 USP6 H. sapiens SDL Slorth 0.982193 View
ENSG00000097007 ABL1 ENSG00000154016 GRAP H. sapiens SDL Slorth 0.982181 View
ENSG00000097007 ABL1 ENSG00000172845 SP3 H. sapiens SDL Slorth 0.982138 View
ENSG00000097007 ABL1 ENSG00000110075 PPP6R3 H. sapiens SDL Slorth 0.982116 View
ENSG00000097007 ABL1 ENSG00000107862 GBF1 H. sapiens SDL Slorth 0.982116 View
ENSG00000097007 ABL1 ENSG00000204843 DCTN1 H. sapiens SDL Slorth 0.982081 View
ENSG00000097007 ABL1 ENSG00000176986 SEC24C H. sapiens SDL Slorth 0.982076 View
ENSG00000097007 ABL1 ENSG00000101421 CHMP4B H. sapiens SDL Slorth 0.982046 View
ENSG00000019582 CD74 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.982043 View
ENSG00000097007 ABL1 ENSG00000115266 APC2 H. sapiens SDL Slorth 0.981996 View
ENSG00000087470 DNM1L ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.981963 View
ENSG00000097007 ABL1 ENSG00000108061 SHOC2 H. sapiens SDL Slorth 0.981955 View
ENSG00000097007 ABL1 ENSG00000213672 NCKIPSD H. sapiens SDL Slorth 0.98191 View
ENSG00000097007 ABL1 ENSG00000163660 CCNL1 H. sapiens SDL Slorth 0.981887 View
ENSG00000097007 ABL1 ENSG00000152601 MBNL1 H. sapiens SDL Slorth 0.981862 View
ENSG00000072422 RHOBTB1 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.981862 View
ENSG00000008853 RHOBTB2 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.981862 View
ENSG00000097007 ABL1 ENSG00000125733 TRIP10 H. sapiens SDL Slorth 0.981849 View
ENSG00000092421 SEMA6A ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.981842 View
ENSG00000072274 TFRC ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.981759 View
ENSG00000097007 ABL1 ENSG00000135424 ITGA7 H. sapiens SDL Slorth 0.98173 View
ENSG00000097007 ABL1 ENSG00000119403 PHF19 H. sapiens SDL Slorth 0.98167 View
ENSG00000097007 ABL1 ENSG00000136758 YME1L1 H. sapiens SDL Slorth 0.981668 View
ENSG00000097007 ABL1 ENSG00000147130 ZMYM3 H. sapiens SDL Slorth 0.981668 View
ENSG00000097007 ABL1 ENSG00000121691 CAT H. sapiens SDL Slorth 0.981668 View
ENSG00000097007 ABL1 ENSG00000180198 RCC1 H. sapiens SDL Slorth 0.981661 View