ABL1

ENSG00000097007 - H. sapiens

Pathways

Go term Description
GO:0000287 magnesium ion binding
GO:0003677 DNA binding
GO:0003785 actin monomer binding
GO:0004515 nicotinate-nucleotide adenylyltransferase activity
GO:0004672 protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005080 protein kinase C binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008022 protein C-terminus binding
GO:0017124 SH3 domain binding
GO:0019905 syntaxin binding
GO:0030145 manganese ion binding
GO:0051015 actin filament binding
GO:0051019 mitogen-activated protein kinase binding
GO:0070064 proline-rich region binding
GO:0005102 receptor binding

Drugs

Drug name Description
BOSUTINIB Tyrosine-protein kinase ABL inhibitor
DASATINIB Tyrosine-protein kinase ABL inhibitor
IMATINIB Tyrosine-protein kinase ABL inhibitor
NILOTINIB Tyrosine-protein kinase ABL inhibitor
PONATINIB Tyrosine-protein kinase ABL inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor

Diseases

Disease Name
CML
ALL
T-ALL

Orthologs

Gene Organism
abl-1 C. elegans
Abl D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000097007 ABL1 ENSG00000111348 ARHGDIB H. sapiens SDL Slorth 0.984319 View
ENSG00000097007 ABL1 ENSG00000131196 NFATC1 H. sapiens SDL Slorth 0.984297 View
ENSG00000097007 ABL1 ENSG00000162302 RPS6KA4 H. sapiens SDL Slorth 0.98427 View
ENSG00000097007 ABL1 ENSG00000113328 CCNG1 H. sapiens SDL Slorth 0.984253 View
ENSG00000006468 ETV1 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.984234 View
ENSG00000097007 ABL1 ENSG00000102471 NDFIP2 H. sapiens SDL Slorth 0.984211 View
ENSG00000097007 ABL1 ENSG00000159200 RCAN1 H. sapiens SDL Slorth 0.984159 View
ENSG00000097007 ABL1 ENSG00000100968 NFATC4 H. sapiens SDL Slorth 0.984156 View
ENSG00000097007 ABL1 ENSG00000143867 OSR1 H. sapiens SDL Slorth 0.984156 View
ENSG00000097007 ABL1 ENSG00000171150 SOCS5 H. sapiens SDL Slorth 0.984154 View
ENSG00000097007 ABL1 ENSG00000158186 MRAS H. sapiens SDL Slorth 0.984141 View
ENSG00000097007 ABL1 ENSG00000133216 EPHB2 H. sapiens SDL Slorth 0.984136 View
ENSG00000097007 ABL1 ENSG00000169926 KLF13 H. sapiens SDL Slorth 0.984061 View
ENSG00000097007 ABL1 ENSG00000143556 S100A7 H. sapiens SDL Slorth 0.984043 View
ENSG00000097007 ABL1 ENSG00000189403 HMGB1 H. sapiens SDL Slorth 0.984028 View
ENSG00000067992 PDK3 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.983988 View
ENSG00000072736 NFATC3 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.983962 View
ENSG00000097007 ABL1 ENSG00000139318 DUSP6 H. sapiens SDL Slorth 0.983956 View
ENSG00000097007 ABL1 ENSG00000160145 KALRN H. sapiens SDL Slorth 0.983932 View
ENSG00000097007 ABL1 ENSG00000128607 KLHDC10 H. sapiens SDL Slorth 0.983923 View
ENSG00000097007 ABL1 ENSG00000177731 FLII H. sapiens SDL Slorth 0.983923 View
ENSG00000097007 ABL1 ENSG00000143322 ABL2 H. sapiens SDL Slorth 0.983885 View
ENSG00000007908 SELE ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.983826 View
ENSG00000097007 ABL1 ENSG00000137265 IRF4 H. sapiens SDL Slorth 0.983771 View
ENSG00000097007 ABL1 ENSG00000125968 ID1 H. sapiens SDL Slorth 0.983739 View
ENSG00000079156 OSBPL6 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.983689 View
ENSG00000077380 DYNC1I2 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.983689 View
ENSG00000097007 ABL1 ENSG00000100721 TCL1A H. sapiens SDL Slorth 0.983664 View
ENSG00000078114 NEBL ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.983663 View
ENSG00000070476 ZXDC ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.983648 View
ENSG00000097007 ABL1 ENSG00000169714 CNBP H. sapiens SDL Slorth 0.983643 View
ENSG00000097007 ABL1 ENSG00000205629 LCMT1 H. sapiens SDL Slorth 0.983624 View
ENSG00000097007 ABL1 ENSG00000160224 AIRE H. sapiens SDL Slorth 0.983615 View
ENSG00000097007 ABL1 ENSG00000154447 SH3RF1 H. sapiens SDL Slorth 0.983578 View
ENSG00000097007 ABL1 ENSG00000166974 MAPRE2 H. sapiens SDL Slorth 0.98357 View
ENSG00000097007 ABL1 ENSG00000185896 LAMP1 H. sapiens SDL Slorth 0.983549 View
ENSG00000097007 ABL1 ENSG00000112242 E2F3 H. sapiens SDL Slorth 0.983538 View
ENSG00000097007 ABL1 ENSG00000184675 AMER1 H. sapiens SDL Slorth 0.98352 View
ENSG00000095397 WHRN ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.98351 View
ENSG00000097007 ABL1 ENSG00000138795 LEF1 H. sapiens SDL Slorth 0.983496 View